Results 151 to 160 of about 1,107,201 (376)
Advanced Functional Materials, EarlyView.We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
Multivariate Analysis for Fault Diagnosis System [PDF]
, 2008 Many multivariate techniques have been applied to diagnose faults such as Principal Component Analysis (PCA), Fisher’s Discriminant Analysis (FDA), and Discriminant Partial Least Squares (DPLS).
Hanaa, E.Sayed +2 more
core
Tailoring the Properties of Functional Materials With N‐Oxides
Advanced Functional Materials, EarlyView.The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich +5 more
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 Integrity of records or data integrity is the most «hot» requirement when assessing documentation systems for compliance with Good Manufacturing Practice (GMP). It's in the center of focus of attention during inspections of pharmaceutical companies. This
I. A. Osmolovskaya +3 more
doaj
Reconfigurable Magnetic Soft Microrobot for Acoustically Triggered Targeted Bacterial Sterilization
Advanced Functional Materials, EarlyView.Reconfigurable magnetic soft microrobots integrate in situ‐grown piezoelectric zinc oxide nanorods that produce reactive oxygen species upon acoustic excitation. Combining magnetically guided transport with thermally induced planar reconfiguration, the microrobots achieve targeted delivery and enhanced bacterial sterilization through efficient on ...
Quan Gao +12 more
wiley +1 more source
Process development for production of non-originator NISTmAb from CHO and NS0 cell lines
mAbsCell lines that produce non-originator versions of the National Institute of Standards and Technology (NIST) monoclonal antibody reference material 8671 (NISTmAb) are invaluable to the biopharmaceutical industry because, unlike typical commercial cell ...
Erica J. Fratz-Berilla +4 more
doaj +1 more source
Don\u27t Try This at Home: The FDA\u27s Restrictive Regulation of Home-Testing Devices [PDF]
, 2017 Over the past forty years, the Food and Drug Administration (FDA) has successfully restricted consumers\u27 access to home-testing applications based on the notion that it should protect individuals from their own reactions to test results. In the 1970s,
Shelby Baird
core +1 more source
Advanced Functional Materials, EarlyView.A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
Regulatory Science Needs for Neonates: A Call for Neonatal Community Collaboration and Innovation
Frontiers in Pediatrics, 2014 Susan K McCune, Yeruk Ager Mulugeta
doaj +1 more source