Results 261 to 270 of about 953,056 (326)

A joint range-angle-velocity estimation algorithm for FDA-MIMO radar based on graph signal processing. [PDF]

Sci Rep
Li Q, Meng A, Liao K, Xie N, Liao X, Chen H, Ghazali KHB.   +6 more
europepmc   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Continuous Glucose Monitoring in Diabetes Care in Saudi Arabia: Addressing Performance Standards and Regulatory Gaps-Literature Review and Consensus Report. [PDF]

J Diabetes Sci Technol
Almehthel M, Alsofiani M, Alzaman N, Alzahrani S, Elbadawi H, Alzubaidi L, Aldawish M, Alotaibi M, Alsabaan F, Aldahash R, Alowairdhi M, Issak ER, Alsifri S.   +12 more
europepmc   +1 more source

Therapeutic Monoclonal Antibodies Approved by FDA in 2023

openalex   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions. [PDF]

MedComm (2020)
Wu Y, Xue R, Luo X, Liao J, Zhang Z, Deng J, Liu T, Li X, Chen ZS, Yin M.   +9 more
europepmc   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Reduced-nicotine cigarettes for smoking cessation and reduction. [PDF]

Cochrane Database Syst Rev
Livingstone-Banks J, Ma C, Klemperer E, Cassidy RN, Jarman H, Hatsukami D, Lindson N, Hartmann-Boyce J.   +7 more
europepmc   +1 more source

Regulatorische Bewertung von recycelten Kunststoffen für Anwendungen mit Lbensmittelkontakt: : eine vergleichende Analyse der EFSA- und FDA -Zulassungsverfahren mit Fokus auf recyceltes Polypropylen

Hauhart-Mitterbauer, Laura Franziska
openalex   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source