Results 21 to 30 of about 1,107,201 (376)

The FDA-approved anti-amyloid-β monoclonal antibodies for the treatment of Alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials

open access: yesEuropean Journal of Medical Research, 2023
Background Alzheimer’s disease (AD) is a worldwide public health problem and is difficult to cure. Drugs aimed at slowing the progression of the disease have been developed, with the Food and Drug Administration (FDA) granting accelerated approval for ...
Wenxue Wu   +7 more
semanticscholar   +1 more source

Evaluation of Methods for Transient Transfection of a Murine Macrophage Cell Line, RAW 264.7

open access: yesBioTechniques, 1999
Monocyte/macrophage cell lines are fastidious cells commonly used in transient transfection experiments. In the course of a study of gene regulation by lipopolysaccharide (LPS), we have compared several methods for DNA-mediated cell transfection to ...
C.D. Thompson   +4 more
doaj   +1 more source

SENTINEL SYSTEM – electronic system for collecting real-world data

open access: yesРеальная клиническая практика: данные и доказательства, 2022
The need to use more and more data to generate evidence in response to new challenges in clinical medicine requires a specific response from the healthcare system. The high pace of development of medicine, the acceleration of the development of new drugs
E. O. Eremenko, M. I. Baranova
doaj   +1 more source

Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs

open access: yesAntimicrobial Agents and Chemotherapy, 2020
Drug repositioning is the only feasible option to immediately address the COVID-19 global challenge. We screened a panel of 48 FDA-approved drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which were preselected by an assay of ...
Sangeun Jeon   +7 more
semanticscholar   +1 more source

Targeted Therapy for Cancers: From Ongoing Clinical Trials to FDA-Approved Drugs

open access: yesInternational Journal of Molecular Sciences, 2023
The development of targeted therapies has revolutionized cancer treatment, offering improved efficacy with reduced side effects compared with traditional chemotherapy.
Ha Yeong Choi, Ji-Eun Chang
semanticscholar   +1 more source

Positron Emission Tomography with [18F]FLT Revealed Sevoflurane-induced Inhibition of Neural Progenitor Cell Expansion in vivo

open access: yesFrontiers in Neurology, 2014
Neural progenitor cell expansion is critical for normal brain development and an appropriate response to injury. During the brain growth spurt, exposures to general anesthetics which either block the N-methyl D-aspartate receptor or enhance the γ ...
Shuliang eLiu   +9 more
doaj   +1 more source

Overview of drugs approved by the FDA in 2022

open access: yesФармация и фармакология (Пятигорск), 2023
The aim of the work is to conduct a review of medications approved by the FDA in 2022.Materials and methods. In searching for the materials to write this review article, bibliographic databases including PubMed, Google Scholar and e-library.ru were ...
D. V. Kurkin   +14 more
doaj   +1 more source

Frequency and Severity of Neutropenia Associated with Food and Drug Administration Approved and Compounded Formulations of Lomustine in Dogs with Cancer. [PDF]

open access: yes, 2015
BackgroundCompounded lomustine is used commonly in veterinary patients. However, the potential variability in these formulations is unknown and concern exists that compounded formulations of drugs may differ in potency from Food and Drug Administration ...
Burton, JH   +5 more
core   +2 more sources

Free Differential Algebras: Their Use in Field Theory and Dual Formulation [PDF]

open access: yes, 1995
The gauging of free differential algebras (FDA's) produces gauge field theories containing antisymmetric tensors. The FDA's extend the Cartan-Maurer equations of ordinary Lie algebras by incorporating p-form potentials ($p > 1$).
Alberto Perotto   +7 more
core   +2 more sources

Seeking out non-public information : sell-side analysts and the freedom of information act [PDF]

open access: yes, 2019
A number of sell-side healthcare analysts gain access to information outside the purview of management through Freedom of Information Act requests to the Food and Drug Administration for records on factory inspections, complaints, and drug and medical ...
Klein, April, Li, Tao, Zhang, Bobo
core   +1 more source

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