Results 31 to 40 of about 812,951 (357)

Time-Range FDA Beampattern Characteristics [PDF]

open access: yesarXiv, 2022
Current literature show that frequency diverse arrays (FDAs) are able of producing range-angle-dependent and time-variant transmit beampatterns, but the resulting time and range dependencies and their characteristics are still not well understood. This paper examines the FDA transmission model and the model for the FDA array factor, considering their ...
arxiv  

Advancing Public Health Using Regulatory Science to Enhance Development and Regulation of Medical Products: Food and Drug Administration Research at the Center for Biologics Evaluation and Research

open access: yesFrontiers in Medicine, 2017
Center for Biologics Evaluation and Research enhances and supports regulatory decision-making and policy development. This work contributes to our regulatory mission, advances medical product development, and supports Food and Drug Administration’s ...
Marc Kusinitz   +2 more
doaj   +1 more source

Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients

open access: yesNature Communications, 2021
SARS-CoV2 infection has been linked to a wide range of clinical severities and the immunopathology is still under intense scrutiny. Here, the authors uncover an association of antibody affinity maturation and plasma IgA levels with clinical outcome in ...
Juanjie Tang   +8 more
doaj   +1 more source

A Spatial Data Focusing and Generalized Time-invariant Frequency Diverse Array Approach for High Precision Range-angle-based Geocasting [PDF]

open access: yesarXiv, 2023
A novel unified frequency diverse array (FDA) and spatial data focusing (SDF) approach is proposed to simultaneously overcome time-variance and precision constraints of conventional FDA in geocasting, i.e., spatially confined broadcasting, scenarios. This paper describes a free space FDA-based SDF (FDA-SDF) system model for 2-dimensional range-angle ...
arxiv  

The Trade-off between Impartiality and Freedom in the 21st Century Cures Act

open access: yesPhilosophy of Medicine, 2021
Randomized controlled trials test new drugs using various debiasing devices to prevent participants from manipulating the trials. But participants often dislike controls, arguing that they impose a paternalist constraint on their legitimate preferences ...
David Fraile Navarro   +2 more
doaj   +1 more source

Unequal Covariance Awareness for Fisher Discriminant Analysis and Its Variants in Classification [PDF]

open access: yesarXiv, 2022
Fisher Discriminant Analysis (FDA) is one of the essential tools for feature extraction and classification. In addition, it motivates the development of many improved techniques based on the FDA to adapt to different problems or data types. However, none of these approaches make use of the fact that the assumption of equal covariance matrices in FDA is
arxiv  

Waveform Optimization with SINR Criteria for FDA Radar in the Presence of Signal-Dependent Mainlobe Interference [PDF]

open access: yesarXiv, 2022
In this paper, we focus on the design of the transmit waveforms of a frequency diverse array (FDA) in order to improve the output signal-to-interference-plus-noise ratio (SINR) in the presence of signal-dependent mainlobe interference. Since the classical multi-carrier matched filtering-based FDA receiver cannot effectively utilize the waveform ...
arxiv  

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Frequency Diverse Arrays (FDAs) vs. Phased Arrays: On the Application of FDAs for Secure Wireless Communications [PDF]

open access: yesarXiv, 2020
Application of range-angle focusing frequency diverse array (FDA) for secure wireless communication has been proposed in recent years. However, it can be proven that the FDAs are not suitable for secure wireless communication and the same properties of the focusing FDA can be obtained by using traditional phased arrays, more effectively.
arxiv  

CYPminer: an automated cytochrome P450 identification, classification, and data analysis tool for genome data sets across kingdoms

open access: yesBMC Bioinformatics, 2020
Background Cytochrome P450 monooxygenases (termed CYPs or P450s) are hemoproteins ubiquitously found across all kingdoms, playing a central role in intracellular metabolism, especially in metabolism of drugs and xenobiotics.
Ohgew Kweon   +12 more
doaj   +1 more source

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