Overview of drugs approved by the FDA in 2022
Фармация и фармакология (Пятигорск), 2023 The aim of the work is to conduct a review of medications approved by the FDA in 2022.Materials and methods. In searching for the materials to write this review article, bibliographic databases including PubMed, Google Scholar and e-library.ru were ...
D. V. Kurkin +14 more
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The FDA “black box” warning on antidepressant suicide risk in young adults: More harm than benefits? [PDF]
, 2019 The decision made in the year 2004 by the U.S. Food and Drug Administration (FDA) to require a boxed warning on antidepressants regarding the risk of suicidality in young adults still represents a matter of controversy.
Anastasia A. +12 more
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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
Nature Immunology, 2020 Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells assembles large complexes called inflammasomes, which activate inflammatory caspases to process cytokines (IL-1β) and gasdermin D (GSDMD).
J. Hu +17 more
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FDA-Approved Trifluoromethyl Group-Containing Drugs: A Review of 20 Years
Processes, 2022 As people around the world regard 2020 as the year of COVID-19, the medical community considers this year to be the second-best year, shared with the year 1996, with respect to the number of drug molecules approved by the US Food and Drug Administration (
Aathira S. Nair +9 more
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SENTINEL SYSTEM – electronic system for collecting real-world data
Реальная клиническая практика: данные и доказательства, 2022 The need to use more and more data to generate evidence in response to new challenges in clinical medicine requires a specific response from the healthcare system. The high pace of development of medicine, the acceleration of the development of new drugs
E. O. Eremenko, M. I. Baranova
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An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy
Molecules, 2021 The large number of emerging antibody-drug conjugates (ADCs) for cancer therapy has resulted in a significant market ‘boom’, garnering worldwide attention.
Juliana T W Tong +3 more
semanticscholar +1 more source
Frequency and Severity of Neutropenia Associated with Food and Drug Administration Approved and Compounded Formulations of Lomustine in Dogs with Cancer. [PDF]
, 2015 BackgroundCompounded lomustine is used commonly in veterinary patients. However, the potential variability in these formulations is unknown and concern exists that compounded formulations of drugs may differ in potency from Food and Drug Administration ...
Burton, JH +5 more
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Free Differential Algebras: Their Use in Field Theory and Dual Formulation [PDF]
, 1995 The gauging of free differential algebras (FDA's) produces gauge field theories containing antisymmetric tensors. The FDA's extend the Cartan-Maurer equations of ordinary Lie algebras by incorporating p-form potentials ($p > 1$).
Alberto Perotto +7 more
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Redox Report, 2020 The β subunit substitutions, F41Y and K82D, in sickle cell hemoglobin (Hb) (βE6 V) provides significant resistance to oxidative stress by shielding βCys93 from the oxidizing ferryl heme.
Wayne Hicks +3 more
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Valuation implications of pharmaceutical companies' R&D regulatory approval notifications [PDF]
, 2013 This paper examines shareholder wealth effects surrounding applications to, and approvals by, the United States Food and Drug Administration (FDA) for firms listed on the New York (NYSE) and London (LSE) stock exchanges.
Hamill, P.A., McIlkenny, P., Opong, K.K.
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