Results 161 to 170 of about 3,880 (180)
Some of the next articles are maybe not open access.
Applied Radiation and Isotopes
As is the case for most solid tumours, chemotherapy remains the backbone in the management of metastatic disease. However, the occurrence of chemotherapy resistance is a cause to worry, especially in bladder cancer. Extensive evidence indicates molecular changes in bladder cancer cells to be the underlying cause of chemotherapy resistance, including ...
Siti Fairus Abdul Sani, David A Bradley
exaly +4 more sources
As is the case for most solid tumours, chemotherapy remains the backbone in the management of metastatic disease. However, the occurrence of chemotherapy resistance is a cause to worry, especially in bladder cancer. Extensive evidence indicates molecular changes in bladder cancer cells to be the underlying cause of chemotherapy resistance, including ...
Siti Fairus Abdul Sani, David A Bradley
exaly +4 more sources
Journal of Dermatological Science, 2012
Keratolytic winter erythema (KWE) or Oudtshoorn skin disease is a rare autosomal dominant monogenic disorder of epidermal keratinisation characterized clinically by cyclical peeling of the palms and soles. Due to a founder effect many KWE families have been identified in South Africa and the gene has been localized to 8p23.1-22, but the causal gene has
Angela, Hobbs +4 more
openaire +2 more sources
Keratolytic winter erythema (KWE) or Oudtshoorn skin disease is a rare autosomal dominant monogenic disorder of epidermal keratinisation characterized clinically by cyclical peeling of the palms and soles. Due to a founder effect many KWE families have been identified in South Africa and the gene has been localized to 8p23.1-22, but the causal gene has
Angela, Hobbs +4 more
openaire +2 more sources
International Journal of Biochemistry and Cell Biology
Chemotherapy against muscle-invasive bladder cancer is increasingly challenged by the prevalence of chemoresistance. The cholesterol biosynthesis pathway has garnered attention in studies of chemoresistance, but conflicting clinical and molecular findings necessitate a clearer understanding of its underlying mechanisms. Recently, we identified farnesyl-
Nurul Amniyyah Azhar
exaly +3 more sources
Chemotherapy against muscle-invasive bladder cancer is increasingly challenged by the prevalence of chemoresistance. The cholesterol biosynthesis pathway has garnered attention in studies of chemoresistance, but conflicting clinical and molecular findings necessitate a clearer understanding of its underlying mechanisms. Recently, we identified farnesyl-
Nurul Amniyyah Azhar
exaly +3 more sources
Association between FDFT1 gene polymorphism and postmenopausal osteoporosis
Panminerva Medica, 2021Liang, He, Shenjin, Wang, Wei, Kong
openaire +2 more sources
Phytomedicine
Artemisitene (ATT) is a natural bioactive compound with anti-breast cancer activity. However, the direct target and clinical efficacy of ATT on breast cancer are still unclear. The current study aimed to identify the target protein and underlying mechanism of ATT in anti-breast cancer.
Dong Chen, Lian-Xiang Luo, Jian Chen
exaly +3 more sources
Artemisitene (ATT) is a natural bioactive compound with anti-breast cancer activity. However, the direct target and clinical efficacy of ATT on breast cancer are still unclear. The current study aimed to identify the target protein and underlying mechanism of ATT in anti-breast cancer.
Dong Chen, Lian-Xiang Luo, Jian Chen
exaly +3 more sources
Current Medicinal Chemistry
Aims: We aimed to develop Ferroptosis-Related Gene (FRG) signatures to predict overall survival (OS) along with disease-free survival (DFS) in individuals with colorectal cancer (CRC). Background: Prediction of CRC prognosis is ...
Lili, Duan +8 more
openaire +2 more sources
Aims: We aimed to develop Ferroptosis-Related Gene (FRG) signatures to predict overall survival (OS) along with disease-free survival (DFS) in individuals with colorectal cancer (CRC). Background: Prediction of CRC prognosis is ...
Lili, Duan +8 more
openaire +2 more sources
Current HIV Research
Introduction: The present study investigated the molecular mechanism by which the transactivator of transcription (Tat) protein of Human Immunodeficiency Virus 1 (HIV-1) acti-vates the replication cycle of Kaposi's Sarcoma-associated Herpesvirus (KSHV). Methods: BCBL-1 cells were initially infected with lentivirus overexpressing HIV-1 Tat.
Qiaozhen Liu +12 more
openaire +1 more source
Introduction: The present study investigated the molecular mechanism by which the transactivator of transcription (Tat) protein of Human Immunodeficiency Virus 1 (HIV-1) acti-vates the replication cycle of Kaposi's Sarcoma-associated Herpesvirus (KSHV). Methods: BCBL-1 cells were initially infected with lentivirus overexpressing HIV-1 Tat.
Qiaozhen Liu +12 more
openaire +1 more source
Archives of Biochemistry and Biophysics
Doxorubicin (DOX) is a classical chemotherapeutic for various cancers that acts by intercalating within the DNA strand and inhibiting the function of topoisomerase, resulting in DNA break-induced apoptosis. Acquired chemoresistance has become a challenge for DOX therapy, but the possible solutions to overcome this problem are under investigation in ...
Trisha Chattopadhyay +3 more
openaire +2 more sources
Doxorubicin (DOX) is a classical chemotherapeutic for various cancers that acts by intercalating within the DNA strand and inhibiting the function of topoisomerase, resulting in DNA break-induced apoptosis. Acquired chemoresistance has become a challenge for DOX therapy, but the possible solutions to overcome this problem are under investigation in ...
Trisha Chattopadhyay +3 more
openaire +2 more sources