Results 81 to 90 of about 352,902 (309)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

FDR Control Results

, 2018
Results of analyses to control the false discovery rate (FDR)
Alexander Van Nynatten (5024018), Belinda SW Chang (68538), Daren C Card (5024015), Todd A Castoe (78700), Ryan K Schott (5024021)   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Actual FDR for a nominal FDR of 0.1.

, 2015
We consider three settings for DE fold changes (estimated from data, fixed at 1.2 and fixed at 1.5), three levels of σ (the estimated value σ=σ˜, half the estimated value σ=0.5σ˜, and no variation σ = 0) and two levels of percentage of DE genes (10% and ...
Yanming Di (91480), Gu Mi (129656)
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

MARKET SHARE DETERMINAN OF ISLAMIC COMMERCIAL BANKS

Finansia
The growth of the market share value of Islamic banks from 2018 to 2023 has fluctuated but tends to increase, even reaching a market share value of 7.44% in 2023.
Lia Safrina, Uswatun Hasanah, Hartanti Dewi, Vita Arum Sari   +3 more
doaj   +1 more source

FDR and food intake

, 2015
FDR of temporarily caged and wild wheatears on Helgond island ...
Schmaljohann, Heiko, Eikenaar, Cas, Tsvey, Arseny, Arseny Tsvey (3251910), Heiko Schmaljohann (3271158), Cas Eikenaar (210253)   +5 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

PROFITABILITY DETERMINANTS OF INDONESIAN ISLAMIC BANKS: FINANCING TO DEPOSIT RATIO AND GOVERNANCE

Finansia
This study aimed to thoroughly examine the impact of financing-to-deposit ratio (FDR) on profitability of Islamic commercial banks in Indonesia, with Good Corporate Governance (GCG) acting as an intervening variable.
Tri Wahyudi, Fiesty Utami, Nur Sabrina
doaj   +1 more source

BANK INTERNAL FACTORS AND PROFIT DISTRIBUTION MANAGEMENT OF SYARIAH BANKS IN INDONESIA

Nurani, 2018
The purpose of this study is to analyze the effect of Capital Adequacy Ratio (CAR), Operation Efficiency (BOPO), Financing to Deposit Ratio(FDR), Proportion of Depositor‟s Funding (PDPK),Purchase Financing (PJB), Profit Sharing ...
Mismiwati
doaj   +1 more source