Results 261 to 270 of about 763,856 (375)

Leonardo Fea nei Carin indipendenti

open access: yesBollettino della Società Geografica Italiana, 1888
Leonardo Fea
doaj  

Talazoparib Formulation Bridging in Cancer Patients—Challenges and the Critical Role of Model‐Informed Drug Development in Approval Despite Failed Bioequivalence

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Talazoparib is a poly(ADP‐ribose) polymerase inhibitor approved for the treatment of breast and prostate cancer. Commercialization of a soft gelatin capsule (SGC) formulation developed post‐approval required a bioequivalence (BE) and food effect (FE) study to bridge SGC with the initial commercial hard capsule (HC) formulation. Study execution
Diane Wang   +10 more
wiley   +1 more source

Lettere dalla Birmania di L. Fea

open access: yesBollettino della Società Geografica Italiana, 1886
Leonardo Fea
doaj  

Conductive Materials and Electrical Stimulation for Auditory Restoration

open access: yesSensory Neuroscience, EarlyView.
Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao   +8 more
wiley   +1 more source

Scale‐Specific Viscoelastic Characterization of Hydrogels: Integrated AFM and Finite Element Modeling

open access: yesSmall, EarlyView.
An integrated multiscale approach reveals distinct viscoelastic responses of hydrogels across length scales. Combining AFM‐based nanoindentation, finite element modeling, and a novel analytical framework, this study enables accurate, scale‐specific mechanical characterization to guide the design of advanced biomaterials. Abstract Viscoelastic hydrogels
Nicole Fertala   +7 more
wiley   +1 more source

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