Results 171 to 180 of about 3,456,580 (406)

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Signaling in The Prefrontal Cortex Modulates Cued Fear Learning, But Not Spatial Working Memory, in Female Rats [PDF]

, 2018
A genetic polymorphism within the gene encoding the pituitary adenylate cyclase- activating polypeptide (PACAP) receptor type I (PAC1R) has recently been associated with hyper-reactivity to threat-related cues in women, but not men, with post-traumatic ...
Gilmartin, Marieke R., Herbst, Matthew R., Kirry, Adam J., Maskeri, Michelle M., Poirier, Sarah E., Rothwell, Amy C., Twining, Robert C.   +6 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

An observational time-series study on the behavioral effects of adjunctive artisanal cannabidiol use by adults with treatment resistant epilepsies

BMC Neurology
Background For approximately 30% of people with epilepsy, seizures are not well-controlled by anti-seizure medication (ASM). This condition, called treatment resistant epilepsy (TRE), is associated with increased morbidity and mortality, and ...
Barbara A. Brett, Matthieu Conroy, Hardik Doshi, Matthew X. Lowe, Sasha Kalcheff-Korn, Heather Jackson   +5 more
doaj   +1 more source

Fear, Conflict, and Union Organizing [PDF]

, 1998
[Excerpt] Workers\u27 fears—of job loss, of strikes, of management retaliation—are well-documented obstacles to successful union organizing. Exploiting these fears is at the heart of employers\u27 union-avoidance strategies.
Hurd, Richard W
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art

Pain, 2000
J. Vlaeyen, S. Linton
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Single-Operator Multi-Port cholecystectomy (SOMP) – technique, safety, and efficacy

BMC Surgery
Background The standard technique of laparoscopic cholecystectomy requires four ports and at least two operators (surgeon and assistant). The Single-Operator Multi-Port (SOMP) technique, wherein the surgeon independently manipulates all four ports using ...
Niraj Balakrishnan, Harold Coley, Kaleb Eaton, William Bukowski, Indy Aronson, Pragatheeshwar Thirunavukarasu   +5 more
doaj   +1 more source

Association between sensory processing and dental fear among female undergraduates in Japan

, 2019
Mika Ogawa, Nozomu Harano, Kentaro Ono, Yukiyo Shigeyama-Tada, Tomoko Hamasaki, Seiji Watanabe   +5 more
openalex   +1 more source