Results 51 to 60 of about 1,900,338 (310)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Spatiotemporal Pattern Selection in a Modified Leslie–Gower Predator–Prey System with Fear Effect and Self-Diffusion

Mathematics
Indirect fear effects profoundly influence predator–prey dynamics by reducing prey reproduction. Whereas previous studies have investigated fear effects or self-diffusion separately in Leslie–Gower models, the novelty of this work lies in their ...
Xintian Jia, Lingling Zhao, Lijuan Zhang, Kunlun Huang   +3 more
doaj   +1 more source

Effects of Anti-Smoking Advertisements on Young People: Role of Gender and Level of Smoking [PDF]

Athens Journal of Mass Media and Communications, 2019
The main argument for using a fear-appeal message is that fear appeal is designed to stimulate anxiety in the audience, with the expectation the audience members will attempt to reduce this anxiety by adopting a specified course of action as suggested in
Hwiman Chung, Euicheol Jung
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Spatiotemporal dynamics of a modified Leslie–Gower predator–prey model: Effects of diffusion and taxis-driven movements on pattern formation

Nonlinear Analysis
In this manuscript, we investigate a Leslie–Gower predator–prey model with Crowley–Martin-type functional response. We also explore the dynamics of reaction–diffusion as well as reaction–diffusion–advection model.
Anand Singh, Sayan Mandal, Pankaj Kumar Tiwari, Balram Dubey   +3 more
doaj   +1 more source

The association between fear of malpractice and burnout among Chinese medical workers: The mediating role of legal consciousness

BMC Psychiatry, 2022
Background As a major reason for defensive medicine, the status and effect of “fear of malpractice” among Chinese medical staff is an important topic that needs to be studied.
Fei Liang, Shu Hu, Youqi Guo
doaj   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Dynamics analysis of a diffusive prey-taxis system with memory and maturation delays

Electronic Journal of Qualitative Theory of Differential Equations
In this paper, a diffusive predator-prey system considering prey-taxis term with memory and maturation delays under Neumann boundary conditions is investigated.
Hongyan Sun, Pengmiao Hao, Jianzhi Cao
doaj   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Signaling in The Prefrontal Cortex Modulates Cued Fear Learning, But Not Spatial Working Memory, in Female Rats [PDF]

, 2018
A genetic polymorphism within the gene encoding the pituitary adenylate cyclase- activating polypeptide (PACAP) receptor type I (PAC1R) has recently been associated with hyper-reactivity to threat-related cues in women, but not men, with post-traumatic ...
Gilmartin, Marieke R., Herbst, Matthew R., Kirry, Adam J., Maskeri, Michelle M., Poirier, Sarah E., Rothwell, Amy C., Twining, Robert C.   +6 more
core   +1 more source