Results 71 to 80 of about 720,969 (306)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Does Fear of Childbirth Predict Emergency Cesarean Section in Primiparous Women?

حیات, 2009
Background & Aim: Effect of women's psychological status on delivery processes is proven. Studies showed that women who experience severe anxiety were more vulnerable for getting emergency cesarean, and physical and psychological complications.
T Negahban, A Ansari
doaj  

Does obstetric violence influence institutional delivery utilization? Prevalence of fear of institutional delivery on subsequent pregnancy among mothers who gave birth in the past 12 months at Honkolo Wabe District, Arsi Zone Ethiopia, 2023AJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: One of the issues that contribute to the increase in home births among mothers is the fear of giving birth in an institution. Although delivery services are free in Ethiopia, about half of women chose not to use them because they were afraid ...
Solomon Seyife Alemu, MSc, Getu Amsalu Erqu, MSc, Dereje Diriba Woyessa, MSc, Lema Fikadu Wedajo, MSc   +3 more
doaj   +1 more source

Factors associated with fear of childbirth in a subsequent pregnancy: a nationwide case–control analysis in Finland

BMC Women's Health, 2023
Background Fear of childbirth can develop due to the concerns or adverse maternal or foetal outcomes experienced in a previous pregnancy. The aim of this study was to examine the main risk factors associated with the development of fear of childbirth ...
Matias Vaajala, Rasmus Liukkonen, Ilari Kuitunen, Ville Ponkilainen, Ville M. Mattila, Maiju Kekki   +5 more
doaj   +1 more source

A review of factors that influence individual compliance with mass drug administration for elimination of lymphatic filariasis. [PDF]

, 2013
BACKGROUND: The success of programs to eliminate lymphatic filariasis (LF) depends in large part on their ability to achieve and sustain high levels of compliance with mass drug administration (MDA). This paper reports results from a comprehensive review
Fischer, Peter U, Krentel, Alison, Weil, Gary J   +2 more
core   +4 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The comparison of fear of childbirth and sense of coherence among low-risk and high-risk pregnancy women

Journal of Education and Health Promotion, 2018
INTRODUCTION: Childbirth fear is one of the major problems during pregnancy and postpartum, and it assesses the sense of management coherence in stress. Therefore, the present study was conducted to compare the association between the sense of coherence ...
Shahla Mohamamdirizi, Marjan Mohamadirizi, Soheila Mohamadirizi   +2 more
doaj   +1 more source

STRATEGIES OF CONSTRUCTING APPEALS IN OBAMA’S VICTORY SPEECH [PDF]

, 2012
One of important things that a speaker should pay attention in delivering a speech is constructing appeals. By constructing appeals in the speech, it will make the well-organized content of speech to be more influencing and convincing.
Hakim, Luqman
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source