Results 81 to 90 of about 104,730 (259)

Fear of Missing Out (FoMO) and Learning Disengagement in College Students

Gadjah Mada Journal of Psychology
Intensive smartphone use driven by fear of missing out (FoMO) is an early indicator of a student’s learning disengagement. Learning disengagement refers to students’ lack of engagement in the learning process due to distractions caused by smartphone use ...
Raudhatur Rahmah, Afriani Afriani, Eka Dian Aprilia, Arum Sulistyani, Zaujatul Amna, Syarifah Faradina   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Why Are Maximizers More Vulnerable to Fear of Missing Out? Exploring the Link Between Maximization and Fear of Missing Out Through Variety-Seeking

SAGE Open
There is a growing body of research on FoMO, yet the causal link between maximization and FoMO remains underexplored. This paper addresses this gap by investigating the mediating role of variety-seeking in the relationship between maximization and FoMO ...
Volkan Doğan, Enis Yakut, Selin Göral Nazlıoğlu, Ali Emre Aydın, Bahadır Ayar, Derya Yalçın Doğan   +5 more
doaj   +1 more source

Resilience and symptoms of depression and anxiety in adolescents: the mediating role of fear of missing out

Current Issues in Personality Psychology
Background This research aimed to determine the relationship of resilience and symptoms of depression and anxiety in Indonesian adolescents, particularly the degree to which the fear of missing out (FoMO) influenced resilience toward symptoms of ...
Annastasia Ediati, Dian V. Sakti Kaloeti, Kurniawan Teguh Martono, Lusi Nur Ardhiani   +3 more
doaj   +1 more source

Fear of Missing Out dan Narsisme

Ganaya : Jurnal Ilmu Sosial dan Humaniora
The advancement of internet technology and social media, particularly Instagram, has significantly impacted students' lives, with Fear of Missing Out (FoMO) and narcissism suspected as driving factors behind Instagram addiction. This research seeks to assess the impact of fear of missing out and narcissism on Instagram addiction among university ...
Nur Kholisah, Aulia Suhesty
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The young and the restless: Socializing trumps sleep, fear of missing out, and technological distractions in first-year college students

International Journal of Adolescence and Youth, 2017
College students are a sleep-deprived population, with first-year students facing a number of specific challenges to sleep. As students transition into and through the first year of college, sleep may be sacrificed for a variety of reasons.
Sue K. Adams, Desireé N. Williford, Annemarie Vaccaro, Tiffani S. Kisler, Alyssa Francis, Barbara Newman   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source