Results 91 to 100 of about 173,462,332 (279)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Assessment of Kinesiophobia in Postoperative Cardiac Patients: A Cross-Sectional Study

Journal Riphah College of Rehabilitation Sciences
Background: Cardiac surgeries are commonly and successfully performed to treat various cardiovascular disorders. Postoperative cardiac rehabilitation is essential to minimize the negative effects of surgery.
Naeem ud Din, Hayat Ullah, Sara Alam, Seema Gul   +3 more
doaj  

Mediating effect of falls efficacy in pain catastrophizing and kinetophobia in patients with lumbar degenerative diseases (跌倒效能在腰椎退行性疾病患者疼痛灾难化与恐动症间的中介效应)

中西医结合护理
Objective To analyze the mediating effect of falls efficacy on pain catastrophism and kinetophobia in patients with lumbar degenerative disease. Methods A total of 146 patients with lumbar degenerative disease admitted to the department of Spine ...
WANG Xiaoying (王小影), SHI Yunong (施雨秾), YU Jie (于杰), YANG Liguo (杨立国), GUO Jingran (郭敬然), MENG Xiaona (孟小娜), TANG Qiqun (唐启群)   +6 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Exposure and the reduction of fear of pain [PDF]

, 2012
This research investigated interoceptive exposure as a treatment option for disabling pain-related fear. Interoceptive exposure was conceptualised as an extension of the Fear Avoidance Model and a literature review highlighted three important areas ...
Taylor, Siobhan Catherine
core  

Prediction of the Level of Response to Pain based on Fear of Death, Fear of Movement, and Personality Traits in the Patients with Chronic Low Back Pain

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019
Background and Objectives: Chronic pain is one of the important problems in medicine. The aim of this research was to predict the level of pain response based on fear of movement, fear of death and the role of personality traits (extraversion, openness ...
Zahra Edalatmehr, Behrouz Atashrouz, Mohammadreza Naeeni Pormahabadi   +2 more
doaj  

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Prevention and management of kinesiophobia after total knee arthroplasty: an evidence-informed narrative review and proposed stepped-care pathway

Frontiers in Rehabilitation Sciences
Kinesiophobia is a potentially modifiable biopsychosocial barrier to recovery after total knee arthroplasty (TKA), yet evidence specific to fear of movement is dispersed across rehabilitation, psychological, nursing, and perioperative literature and is ...
Lina Liu, Lina Liu, Haobo Sun, Li Ni
doaj   +1 more source

Fear of movement in patients with cardiovascular disease

, 2022
Cardiovascular diseases are the leading cause of death globally. Physical activity improves functional capacity and quality of life, and is a cornerstone of secondary prevention of cardiovascular disease and a core component of cardiac rehabilitation.
openaire   +2 more sources

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source