Results 241 to 250 of about 301,580 (307)

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

British Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia, Huang Xingxing, Jin Lu, Wang Ruwei   +3 more
wiley   +1 more source

Experiences and long-term repercussions of perinatal grief in women after perinatal bereavement: a meta-ethnography. [PDF]

Front Psychiatry
Beato BVG, Machado-Kayzuka GC, Neris RR, Payne E, de Andrade Alvarenga W, Leite ACAB, Silva-Rodrigues FM, Polita NB, deMontigny F, Silverio SA, Nascimento LC.   +10 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Convergent validity between two questionnaires that evaluate fear of childbirth validated in spanish: childbirth fear questionnaire (CFQ-e) and Wijma delivery expectancy questionnaire (WDEQ-A-Sp). [PDF]

BMC Pregnancy Childbirth
Míes-Padilla S, Pallarés-Egea E, Muñoz-Maza N, Garay-Trullos P, González-de la Torre H, Martín-Martínez A.   +5 more
europepmc   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Perspectives of obstetricians and midwives on the preference for caesarean deliveries: a qualitative exploration in Andhra Pradesh, India. [PDF]

BMC Pregnancy Childbirth
Gavvala NB, M BT, Pandey AK, Samal J.
europepmc   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Pregnant Women's Experiences of Stress During the COVID-19 Pandemic: A Qualitative Study. [PDF]

Healthcare (Basel)
Reid CN, Salinas-Miranda A, Vamos C, Fryer Segro K, Beckstead J, Sappenfield WM.   +5 more
europepmc   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Navigating the depths of primiparous's birth perceptions: understanding vaginal birth through metaphors. [PDF]

BMC Pregnancy Childbirth
Sayar SE, Apay SE.
europepmc   +1 more source