Results 71 to 80 of about 175,733,795 (285)

City of fear

open access: yes, 2017
Urban problems have roots in much more abstract issues than only urban design. To understand this, we must cross the approaches of sociologists, politicians, historians, psychologists or criminologists, to name a few.
City of Fear
core  

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Determining the Concerns of Breast Cancer Survivors to Inform Practice

open access: yesAsia-Pacific Journal of Oncology Nursing, 2020
Objective: Breast cancer is the most common cancer in women across all ethnicities, accounting for almost one in three incident cancers in female, and the leading cause of mortality in Singapore.
Gek Phin Chua   +3 more
doaj   +1 more source

Fear of cancer recurrence, anxiety and depressive symptoms in adolescent and young adult cancer patients

open access: yes, 2019
Hengwen Sun,1,* Yuan Yang,2,3,* Jingying Zhang,3,* Ting Liu,3,* Hongmei Wang,4 Samradhvi Garg,5 Bin Zhang31Department of Radiotherapy, Cancer Center, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences ...
Yang Y   +6 more
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

The interconnectedness of fear of cancer recurrence components: A network approach.

open access: yesHealth Psychology
While nearly 60% of cancer survivors report a heightened fear of cancer recurrence (FCR), not all of them experience functional impairment and want professional psychological care. We applied the network approach to study how different components of FCR (symptoms, triggers, perceived risk, and coping strategies) are interconnected to both FCR severity ...
Melanie P. J. Schellekens   +6 more
openaire   +3 more sources

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Association Between Maladaptive Cognitive Emotion Regulation and Fear of Cancer Recurrence in Breast Cancer Patients With a History of Suicide Attempts: A Cross‐Sectional Study

open access: yesCancer Medicine
Objective To investigate the relationship between maladaptive cognitive‐emotional regulation and fear of cancer recurrence in breast cancer patients with a history of suicide attempts.
XinWei Zhang, Hui Tan
doaj   +1 more source

Conceptualizing fear of progression in cardiac patients: Advancing our understanding of the psychological impact of cardiac illness

open access: yesHeart and Mind
Background: An emerging area of psycho-cardiology explores fear of disease progression in cardiac patients, following extensive research of this topic in psycho-oncology. Novel interventions that target cardiac fear of progression(FoP) may be valuable in
Sarah T Clarke   +5 more
doaj   +1 more source

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