Results 81 to 90 of about 2,391,444 (295)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Feasibility Study for Social and General Facilities [PDF]

open access: yes, 2018
The increasing number of population growth affects the emergence of problems in Perumnas Tanjung Karang Permai to be more complex, one of them is situation problem, availability of social facilities and public facilities.
Fibrianti, B. S. (Baiq)   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cytisine Use Vs Nicotine Replacement Therapy in Relapsed Smokers with Heart Disease: Feasibility Results from a Pilot Randomized Trial

open access: yesCJC Open
Background: Cytisine use has proven efficacy for smoking cessation. We plan to investigate whether cytisine use is effective for relapse recovery and conducted a pilot randomized trial to assess the feasibility of a definitive trial.
Hassan Mir, MD, MHI, MPH, FRCPC, FACP   +8 more
doaj   +1 more source

Feasibility of Utilizing Virtual Education from the viewpoints of Professors,Students and Information technology Staff (IT) in Guilan University of Medical Sciences [PDF]

open access: yesPizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī, 2018
Introduction: Virtual education is an electronic teaching method that provides learners with access to education in every situation. This study examines the possibility, facilitators and barriers of   utilizing virtual education in Guilan University of ...
A Saberi, E Kazempour, A Porkar
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Feasibility study

open access: yesCOBE Business Review, 2019
This feasibility study evaluates the viability of JAKIV Company, a start-up partnership planning to produce and market Ecoalily, an all-natural, eco-friendly facial scrub made from locally sourced ingredients including waterlily charcoal, aloe vera, honey, lemongrass extract, rosemary oil, vitamin E, and grapefruit seed extract.
Josiah Natividad   +4 more
  +4 more sources

Adaptation and feasibility assessment of a dating violence prevention program for girls in foster care

open access: yesPsicologia: Reflexão e Crítica
Background Dating violence in adolescence is a serious public health issue due to its significant impact on mental health and its significant predictive value for intimate partner violence in adulthood.
Julliane Quevedo de Moura   +5 more
doaj   +1 more source

Lunar nuclear power feasibility study [PDF]

open access: yes
Based on review of literature and on limited examination of nuclear power systems now proposed for space applications, a nuclear fission reactor powered system should be seriously considered as the first large (order of 50 kWe or greater) power system to
Erdman, C. A., Tran, T.
core   +1 more source

Walley School Community Arts Center Feasibility Study: Appendices [PDF]

open access: yes, 2012
Having a large capacity (over 300 seats) in Walley School demands a major investment in space and cost. Taking this into consideration, the business planning team conducted research and spoke with several individuals in an attempt to inventory and assess
Galvin, Katelyn   +4 more
core   +1 more source

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