Results 31 to 40 of about 130,168 (265)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Advances and Future Prospects of Pigment Deposition in Pigmented Rice
PlantsPigmented rice, particularly the black and red varieties, is popular due to its better nutritional value. Anthocyanins and proanthocyanidins are two major flavonoid subcategories with broad physiological functions and therapeutic significance.
Hong Lang +3 more
doaj +1 more source
Convergence Research Directions in Cognitive Sensor Networks for Elderly Housing Design
International Journal of Distributed Sensor Networks, 2015 As part of resolving the issue related to super-aging society, various information systems for the elderly care have been developed utilizing cognitive sensor networks. However, many sensor network-based systems cognizing radios, resources, environments,
Shinil Suh, Byung-Seo Kim, Jae Hee Chung
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
New Feasibility Conditions for Directed Strongly Regular Graphs
The Electronic Journal of Combinatorics, 2017 We prove two results for directed strongly regular graphs that have an eigenvalue of multiplicity less than $k$, the common out-degree of each vertex. The first bounds the size of an independent set, and the second determines an eigenvalue of the subgraph on the out-neighborhood of a vertex. Both lead to new nonexistence results for parameter sets.
Hobart, Sylvia A., Williford, Jason
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
HYBRID METHODOLOGY OF NONLINEAR GOAL PROGRAMMING
Acta Economica, 2003 What we demonstrate here is a nonlinear goal-programming (NLCP) algorithm based on original hybrid connection of the modified simplex method of goal programming, gradient method of feasible directions and method of optimal displacement size finding ...
Лазо Рољић, PhD
doaj
Weak and Strong Superiorization: Between Feasibility-Seeking and Minimization
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015 We review the superiorization methodology, which can be thought of, in some cases, as lying between feasibility-seeking and constrained minimization. It is not quite trying to solve the full edged constrained minimization problem; rather, the task is to ...
Censor Yair
doaj +1 more source