Results 151 to 160 of about 1,514,414 (296)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Optimization and Hardware Implementation of SYBA-An Efficient Feature Descriptor
, 2019 Feature detection, description and matching are crucial steps in many computer vision algorithms. These rely on feature descriptors to be able to match image features across sets of images.
Fuller, Samuel Gaylin
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Convex-based lightweight feature descriptor for Augmented Reality Tracking. [PDF]
PLoS OneS I, Clement J C.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Accelerator implementation for image feature descriptor matching
, 2017 碩士本論文提出以多重解析全域搜尋之影像特徵描述子匹配演算法為基礎，以硬體描述語言實現影像特徵描述子匹配加速器，並應用於影像處理中的物件辨識及追蹤。在影像辨識與追蹤的研究中，常需要找出影像中物體模型的特徵點並做兩張影像的特徵點匹配運算。當特徵點的維度過高時，要比對兩邊的特徵資料需要花費較多的運算時間，而無法達到物件追蹤上的即時性。而多重解析全域搜尋之影像特徵描述子匹配演算法在這匹配議題上有著不錯的改善效果，此匹配演算法透過降維的方式將特徵描述子向量建立成一張多重解析表 ...
陳秉弘;Chen, Ping-Hung
core
Corrupted Point Cloud Classification Through Deep Learning with Local Feature Descriptor. [PDF]
Sensors (Basel)Wu X +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source