Results 101 to 110 of about 2,151,311 (285)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Gear Degradation Study Using Statistical Time Features and Shallow Neural Networks

open access: yesIEEE Access
Gears are widely recognized as crucial components for power connections and transmission owing to their substantial loading capacity, transmission efficiency, and consistent power output.
Shahil Kumar   +4 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Short-Term Water Demand Forecasting Using Machine Learning Approaches in a Case Study of a Water Distribution Network Located in Italy

open access: yesEngineering Proceedings
Machine learning’s application in short-term water demand forecasting remains a pivotal area of research in water distribution system studies. This investigation reveals a distinctive distribution pattern for the daily demand following dataset ...
Qidong Que   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

A knowledge‐based materials descriptor for compositional dependence of phase transformation in NiTi shape memory alloys

open access: yesMaterials Genome Engineering Advances
This study presents ∆τ, a novel descriptor that captures the compositional dependence of phase transformation temperature (Ap) in NiTi‐based shape memory alloys (SMAs).
Cheng Li   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

FiSC: A Novel Approach for Fitzpatrick Scale-Based Skin Analyzer’s Image Classification

open access: yesIEEE Access
The Fitzpatrick scale is a widely used tool in dermatology for categorizing skin types based on melanin levels and sensitivity to ultraviolet light. The primary objective of this study is to enhance the accuracy of Fitzpatrick scale classification by ...
Guillermo Crocker Garcia   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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