Results 221 to 230 of about 6,466,227 (249)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Multi-omics feature engineering driven by biomedical foundation models improves drug response prediction for inflammatory bowel disease patients. [PDF]

Sci Rep
Gardiner LJ, Kelly J, Evans A, Checkley S, Bingham K, Macluskie G, Bunton D.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Robust coffee plant disease classification using deep learning and advanced feature engineering techniques. [PDF]

PeerJ Comput Sci
Ardah H, Alrahhal M, M Abd-Elhafiez W, Trabay D.   +3 more
europepmc   +1 more source

Omics-based Cancer Prognosis Across Ethnic Groups: From Feature Engineering to Disparity Detection and Mitigation. [PDF]

IEEE Trans Artif Intell
Sharma T, Verma NK, Cui Y.
europepmc   +1 more source

Explainable AI based cervical cancer prediction using FSAE feature engineering and H2O AutoML. [PDF]

Sci Rep
Karthikeyan P, Malaserene I, Deepakraj E.   +2 more
europepmc   +1 more source

InteracTor: Feature engineering and explainable AI for profiling protein structure-interaction-function relationships. [PDF]

PLoS Comput Biol
Silva JCF, Schuster L, Sexson N, Erdem M, Hulke R, Kirst M, Resende MFR, Dias R.   +7 more
europepmc   +1 more source

HEPAD: enhancing hemolytic peptide prediction with adaptive feature engineering and diverse sequence descriptors. [PDF]

BMC Bioinformatics
Chen SH, Yu JC, Lin YH, Kuo SC, Ni K, Chen CT.   +5 more
europepmc   +1 more source

Multi-family wavelet-based feature engineering method for short-term time series forecasting. [PDF]

Sci Rep
Yemets K, Izonin I, Mitoulis SA.
europepmc   +1 more source