Results 181 to 190 of about 1,444,731 (307)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

An improved feature extraction algorithm for EEG-based driving fatigue recognition. [PDF]

Sci Rep
Geng X, Hu W, Liang Q, Chen C, Zhang X, Yu P, Bao J.   +6 more
europepmc   +1 more source

An Effective Randomized Algorithm for Hyperspectral Image Feature Extraction

Jinhong Feng, Rui Yan, Gaohang Yu, Zhongming Chen   +3 more
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cotton leaf disease detection model focusing on small targets and comprehensive feature extraction. [PDF]

Sci Rep
Abudukelimu H, Zhang G, Abulizi A, Ye J, Musideke M, Shi Y, Awudan G.   +6 more
europepmc   +1 more source

Automated Brain Lobe Segmentation and Feature Extraction from Multiple Sclerosis Lesions Using Deep Learning

Nada Haj Messaoud, Rim Ayari, Asma Ben Abdallah, Mohamed Hédi Bedoui   +3 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

A Comparative Survey of Vision Transformers for Feature Extraction in Texture Analysis. [PDF]

J Imaging
Scabini L, Sacilotti A, Zielinski KM, Ribas LC, De Baets B, Bruno OM.   +5 more
europepmc   +1 more source

Research on Sub-pixel Edge Feature Extraction and Measurement Based on Polynomial Fitting

, 2022
Lexin Cao, Wenli Geng, Hanwen Zhang, Xiaodan Chang, Yijun Tang   +4 more
openalex   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source