Results 221 to 230 of about 1,407,173 (272)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Cross-regional radiomics: a novel framework for relationship-based feature extraction with validation in Parkinson's disease motor subtyping. [PDF]

BioData Min
Hosseini MS, Aghamiri SMR, Panahi M.
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Leveraging advanced feature extraction for improved kidney biopsy segmentation. [PDF]

Front Med (Lausanne)
Wajeeh Us Sima M, Wang C, Arshad M, Shaikh JA, Alkhalaf S, Alturise F.   +5 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

A Novel Approach of Pig Weight Estimation Using High-Precision Segmentation and 2D Image Feature Extraction. [PDF]

Animals (Basel)
Chen Y, Li Z, Yin L, Kuang Y.
europepmc   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Unsupervised feature extraction using deep learning empowers discovery of genetic determinants of the electrocardiogram. [PDF]

Genome Med
Sieliwonczyk E, Sau A, Patlatzoglou K, McGurk KA, Pastika L, Thami PK, Mangino M, Zheng SL, Powell G, Curran L, Buchan RJ, Theotokis P, Peters NS, Loeys B, Kramer DB, Waks JW, Ng FS, Ware JS.   +17 more
europepmc   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

An Mcformer encoder integrating Mamba and Cgmlp for improved acoustic feature extraction. [PDF]

Sci Rep
Yolwas N, Li Y, Sun L, Peng J, Sun Z, Wei Y, Cai Y.   +6 more
europepmc   +1 more source