Results 61 to 70 of about 2,887,511 (291)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On Using Physical Analogies for Feature and Shape Extraction in Computer Vision

open access: yes, 2011
There is a rich literature of approaches to image feature extraction in computer vision. Many sophisticated approaches exist for low- and for high-level feature extraction but can be complex to implement with parameter choice guided by experimentation ...
Hurley, David   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

JamesMulqueeney/Automated-3D-Feature-Extraction: Automated-3D-Feature-Extraction

open access: yes
<p>Corresponds to the following paper: How many specimens make a sufficient training set for automated 3D feature extraction?</p ...
James Mulqueeney
core   +1 more source

EEG signal classification using wavelet feature extraction and neural networks [PDF]

open access: yes, 2006
Decision support systems have been utilised since 1960, providing physicians with fast and accurate means towards more accurate diagnoses and increased tolerance when handling missing or incomplete data.
Vassilis Kodogiannis   +5 more
core   +1 more source

Multi-Label Feature Extraction Method Relied on Feature-Label Dependence Auto-encoder

open access: yesJisuanji kexue yu tansuo, 2020
In multi-label learning, how to deal with high-dimensional features has always been one of the research difficulties. The feature extraction algorithm can effectively solve the problem of classification performance degra-dation caused by high ...
CHENG Yusheng, LI Zhiwei, PANG Shufang
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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