Results 131 to 140 of about 2,643,411 (303)

MDCF-Net: Multiscale Dual-Domain Collaborative-Aware Feature Fusion Network for Hyperspectral and Multispectral Image Fusion

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Deep learning-based image fusion methods have achieved remarkable progress in the fusion task of low-resolution hyperspectral images (LR-HSI) and high-resolution multispectral images (HR-MSI).
Shuaiqi Liu   +6 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Mean-Shift Tracking Algorithm Based on Adaptive Fusion of Multi-feature

open access: yes, 2015
The classic mean-shift tracking algorithm has achieved success in the field of computer vision because of its speediness and efficiency. However, classic mean-shift tracking algorithm would fail to track in some complicated conditions such as some parts ...
Xiao YH(肖阳辉)   +3 more
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Application of Improved DNN Algorithm Based on Feature Fusion in Fine-Grained Image Recognition

open access: yesIEEE Access
Fine-grained image recognition is a research highlight in the computer vision. Compared with traditional image classification tasks, it places more emphasis on distinguishing objects with similar appearance features but belonging to different categories.
Jiongguang Zhu, Wei Zhang
doaj   +1 more source

Feature Fusion Based SVM Classifier for Protein Subcellular Localization Prediction

open access: yes, 2016
For the importance of protein subcellular localization in different branches of life science and drug discovery, researchers have focused their attentions on protein subcellular localization prediction.
Ben Islam, Md Khaled   +3 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Cross-Domain Feature Fusion Network: A Lightweight Road Extraction Model Based on Multi-Scale Spatial-Frequency Feature Fusion

open access: yesApplied Sciences
Road extraction is a key task in the field of remote sensing image processing. Existing road extraction methods primarily leverage spatial domain features of remote sensing images, often neglecting the valuable information contained in the frequency ...
Lin Gao, Tianyang Shi, Lincong Zhang
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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