Results 61 to 70 of about 10,702 (264)

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

open access: yesAdvanced Science, EarlyView.
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

open access: yesAdvanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su   +5 more
wiley   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang   +5 more
wiley   +1 more source

On the issue of the conceptual sphere in cognitive linguistics

open access: yesStudia Humanitatis
Many modern works in the field of linguistics feature three main terms: cognitive linguistics, concept and conceptual sphere. Modern researchers, as a rule, consider the concept and the conceptual sphere as part of the concepts of cognitive linguistics ...
Vekilova Naila Janbakhish qizi
doaj  

The Acquisition of Directionals in Two Mayan Languages

open access: yesFrontiers in Psychology, 2019
We use the comparative method of language acquisition research in this article to investigate children’s expression of directional clitics in two Eastern Mayan languages – K’iche’ and Mam (Pye and Pfeiler, 2014; Pye, 2017).
Clifton Pye, Barbara Pfeiler
doaj   +1 more source

CoSP: Reconfigurable Metamaterial Inverse Design via Contrastive Pretrained Large Language Model

open access: yesAdvanced Science, EarlyView.
In this work, CoSP (contrastive multi‐state pretrain), an intelligent inverse design method for reconfigurable metamaterials based on a contrastive pretrained large language model, is proposed. Numerical experiments demonstrate that CoSP can design reconfigurable metamaterial structures for multi‐state, multi‐band optical responses, showing great ...
Shujie Yang   +4 more
wiley   +1 more source

Deceptive Reviews Detection Based on Semi supervised Learning Algorithm

open access: yes工程科学与技术, 2014
:Machine learning methods were presented to identify deceptive reviews.With the integration of knowledge from computational linguistics and psycholinguistics,supervised method was developed to evaluate the performance of different feature modelings,and ...
任亚峰, 姬东鸿, 尹兰
doaj  

The atlas of the Balkan linguistic area program [PDF]

open access: yesBalcanica
This article presents the Atlas of the Balkan Linguistic Area (ABLA), a French- Russian research program that created an online database of language contact phenomena documented in the languages of the Balkans.
Adamou Evangelia, Sobolev Andrey N.
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

Polysemy of the Postposition içinde in Turkish: An Analysis within the Framework of Cognitive Linguistics

open access: yesDilbilim Araştırmaları Dergisi
Cognitive linguistics, which places form and meaning in an integrated and relational scheme, considers polysemy as a natural and inherent feature of language.
Ayşe Eda GÜNDOĞDU
doaj   +1 more source

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