Results 211 to 220 of about 3,367,886 (347)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Fine-grained sketch-based image retrieval by matching deformable part models

, 2014
(c) 2014. The copyright of this document resides with its authors. It may be distributed unchanged freely in print or electronic forms.© 2014. The copyright of this document resides with its authors.
Song, YZ, Timothy M. Hospedales, Li, Y, Yi Li, Shaogang Gong, Hospedales, TM, Gong, S, Yi-zhe Song   +7 more
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Robust Extrinsic Calibration of Multiple RGB-D Cameras with Body Tracking and Feature Matching. [PDF]

Sensors (Basel), 2021
Lee SH, Yoo J, Park M, Kim J, Kwon S.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Evaluation of an Automatic Cephalometric Superimposition Method Based on Feature Matching. [PDF]

J Imaging Inform Med
Zhao L, Huang J, Tang M, Zhang X, Xiao L, Tao R.   +5 more
europepmc   +1 more source

metabCombiner: Paired Untargeted LC-HRMS Metabolomics Feature Matching and Concatenation of Disparately Acquired Data Sets. [PDF]

Anal Chem, 2021
Habra H, Kachman M, Bullock K, Clish C, Evans CR, Karnovsky A.   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

FmCFA: a feature matching method for critical feature attention in multimodal images. [PDF]

Sci Rep
Liao Y, Wu X, Liu J, Liu P, Pan Z, Duan Q.   +5 more
europepmc   +1 more source

Feature Matching Combining Radiometric and Geometric Characteristics of Images, Applied to Oblique- and Nadir-Looking Visible and TIR Sensors of UAV Imagery. [PDF]

Sensors (Basel), 2021
Jang H, Kim S, Yoo S, Han S, Sohn HG.
europepmc   +1 more source