Results 91 to 100 of about 1,793,798 (289)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Feature Ranking for Total Ordering Ranking Problems

Proceedings of the 2010 International Conference on E-Business Intelligence, 2010
In this paper, we first introduce the development of learning to rank and discuss the problems existing in this field especially the ignorance of total ordering ranking. For dealing with the total ordering ranking problem, we assume a method “feature ranking”. Based the assumption, we design two algorithms: Feature Rank and BL-FeatureRank.
Daniel Zeng, Yongqing Wang
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Feature Selection with the Boruta Package [PDF]

This article describes a R package Boruta, implementing a novel feature selection algorithm for finding \emph{all relevant variables}. The algorithm is designed as a wrapper around a Random Forest classification algorithm.
Witold R. Rudnicki, Miron B. Kursa
core  

Intelligent feature based resource selection and process planning [PDF]

, 2012
Lien vers la version éditeur: https://www.inderscience.com/books/index.php?action=record&rec_id=755&chapNum=3&journalID=1022&year=2010This paper presents an intelligent knowledge-based integrated manufacturing system using the STEP feature-based ...
MARTIN, Patrick, ZIZ, William, SIADAT, Ali, SADEGHI, Samira, SADEGHI, Mohsen   +4 more
core  

Feature ranking for the Full Oklahoma dataset.

, 2022
Feature ranking for the Full Oklahoma dataset.
Rachel Bennett (7649594), Alisse Hauspurg (12360105), Zuber D. Mulla (8624097), Pavan Parikh (12360102), Talayeh Razzaghi (2793934)   +4 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Feature ranking for the Full Texas dataset.

, 2022
Feature ranking for the Full Texas dataset.
Rachel Bennett (7649594), Alisse Hauspurg (12360105), Zuber D. Mulla (8624097), Pavan Parikh (12360102), Talayeh Razzaghi (2793934)   +4 more
core   +1 more source

Compressive Sampling and Feature Ranking Framework for Bearing Fault Classification With Vibration Signals

IEEE Access, 2018
Failures of rolling element bearings are amongst the main causes of machines breakdowns. To prevent such breakdowns, bearing health monitoring is performed by collecting data from rotating machines, extracting features from the collected data, and ...
Hosameldin Ahmed, Asoke K. Nandi
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source