Results 141 to 150 of about 57,862 (263)
Accurate characterization of cellular states is the foundation for precise prediction of drug sensitivity in cancer cell lines, which in turn is fundamental to realizing precision oncology.
Jiashuo Wu +10 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Accurate and robust feature-based homography estimation using HALF-SIFT and feature localization error weighting [PDF]
The goal of homography estimation is to find global transformation between two images of the same scene taken from different viewpoints. The feature-based homography estimation method uses a local feature extractor, a RANSAC-like method and the Levenberg-
Zhao CY(赵春阳), Zhao HC(赵怀慈)
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Feature Extraction Without Edge Detection [PDF]
Information representation is a critical issue in machine vision. The representation strategy in the primitive stages of a vision system has enormous implications for the performance in subsequent stages.
Chaney, Ronald D.
core
The precise tie-points (TPs) on synthetic aperture radar (SAR) images are a critical cornerstone in the global digital elevation model (DEM) and digital ortho map (DOM) production process. While there are abundant studies on SAR TPs matching, improvement
Yifan Zhang +8 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Feature-based designer's intents [PDF]
Feature-based modelling is considered an improvement on existing CAD systems. Features are considered to be a medium that carries designer’s intents, but neither features nor designer’s intent have widely accepted definitions.
Marcelo da Silva Hounsell (7201709) +1 more
core

