Results 131 to 140 of about 796,511 (318)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Intelligent feature based resource selection and process planning

, 2012
Lien vers la version éditeur: https://www.inderscience.com/books/index.php?action=record&rec_id=755&chapNum=3&journalID=1022&year=2010This paper presents an intelligent knowledge-based integrated manufacturing system using the STEP feature-based ...
MARTIN, Patrick, ZIZ, William, SIADAT, Ali, SADEGHI, Samira, SADEGHI, Mohsen   +4 more
core  

Large-scale attribute selection using wrappers

, 2009
Scheme-specific attribute selection with the wrapper and variants of forward selection is a popular attribute selection technique for classification that yields good results. However, it can run the risk of overfitting because of the extent of the search
Andreas Karwath, Martin Gutlein, Gutlein, Martin, Hall, Mark A., Karwath, Andreas, Mark Hall, Eibe Frank, Karwath, Andreas; id_orcid, Frank, Eibe   +8 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Feature Selection Algorithm for High Dimensional Data using Fuzzy Logic

, 2013
Feature subset selection is an effective way for reducing dimensionality removing irrelevant data increasing learning accuracy and improving results comprehensibility This process improved by cluster based FAST Algorithm and Fuzzy Logic FAST ...
Dr. J.Vellingiri, T.Jaga Priya Vathana, C.Saravanabhavan   +2 more
core  

A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification

, 2008
Wei N, Flaschel E, Friehs K, Nattkemper TW. A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classification. BMC Bioinformatics.
Wei, Ning, Flaschel, Erwin, Nattkemper, Tim Wilhelm ; https://orcid.org/, Nattkemper Tim, Flaschel Erwin, Ning Wei, Tim Nattkemper, Wei Ning, Friehs, Karl, Friehs Karl, Karl Friehs, Erwin Flaschel   +11 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Factor Investment or Feature Selection Analysis?

Mathematics
This study has made significant findings in A-share market data processing and portfolio management. Firstly, by adopting the Lasso method and CPCA framework, we effectively addressed the problem of multicollinearity among feature indicators, with the ...
Jifang Mai, Shaohua Zhang, Haiqing Zhao, Lijun Pan   +3 more
doaj   +1 more source

Feature Selection for Interpretable Machine Learning models

, 2022
LAUREA MAGISTRALEL’arrivo dei big data da fonti diverse ha avuto un grande impatto anche negli studi ambientali, tra i quali l’analisi dell’inquinamento dell’aria.
Bresciani, Matteo
core