A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
On Two-Stage Feature Selection Methods for Text Classification
IEEE Access, 2018 Text classification is a high dimensional pattern recognition problem where feature selection is an important step. Although researchers still propose new feature selection methods, there exist many two-stage feature selection methods combining existing ...
Alper Kursat Uysal
doaj +1 more source
Feature selection with ensemble learning for prostate cancer diagnosis from microarray gene expression [PDF]
, 2021 Abdu Gumaei +4 more
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The Effect of Feature Selection on Machine Learning Classification
JOIV: International Journal on Informatics VisualizationHigh-dimensional datasets can lead to overfitting and computationally expensive model building on machine learning. This study uses a dimensionality reduction technique, namely feature selection techniques, to overcome these problems.
Jasman Pardede, Rio Dwianto
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Mapping the Growing Stem Volume of the Coniferous Plantations in North China Using Multispectral Data from Integrated GF-2 and Sentinel-2 Images and an Optimized Feature Variable Selection Method [PDF]
, 2021 Xinyu Li +3 more
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
On Supervised Feature Selection from High Dimensional Feature Spaces
APSIPA Transactions on Signal and Information Processing, 2022 Yijing Yang +3 more
doaj +1 more source