Results 61 to 70 of about 735,517 (309)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Auto Encoder Fixed-Target Training Features Extraction Approach for Binary Classification Problems
, 2023 The main issues with machine learning-based feature extraction techniques are the requirement of extensive domain-level knowledge, experience, and the need to be supported by large amounts of data that are sometimes not available.
Mejri , M. +3 more
core +1 more source
Extraction of Coal and Gangue Geometric Features with Multifractal Detrending Fluctuation Analysis
Applied Sciences, 2018 The separation of coal and gangue is an important process of the coal preparation technology. The conventional way of manual selection and separation of gangue from the raw coal can be replaced by computer vision technology.
Kai Liu, Xi Zhang, YangQuan Chen
doaj +1 more source
COVID-19 Tweets Classification Based on a Hybrid Word Embedding Method
Big Data and Cognitive Computing, 2022 In March 2020, the World Health Organisation declared that COVID-19 was a new pandemic. This deadly virus spread and affected many countries in the world.
Yosra Didi, Ahlam Walha, Ali Wali
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Volatolomics for Anticipated Diagnosis of Cancers with Chemoresistive Vapour Sensors: A Review
ChemosensorsThe anticipated diagnosis of cancers and other fatal diseases from the simple analysis of the volatiles emitted by the body (volatolome) is getting closer and closer from becoming reality.
Abhishek Sachan +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Comparison Between Shape-Based And Area-Based Features Extraction For Java Character Recognition [PDF]
, 2015 Java language is one of the local languages are widely used in Indonesia. Java language is widely used by resident of the island of Java. Java language has special character called Java character.
Adipranata, Rudy +3 more
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