Results 31 to 40 of about 35,270 (248)

Efficacy and Safety of In-Asia-Manufactured rhG-CSF 300 mcg As Primary Prophylaxis for Prevention of CHOP Chemotherapy-induced Severe Neutropenia in Elderly Patients with Lymphoma Non-Hodgkin

Indonesian Journal of Cancer, 2009
We conducted open label, non-comparative trial in patients aged > 60 with advanced and intermediate-grade NonHodgkin Lymphoma (NHL) (stadium II, III, IV) to evaluate the efficacy and safety of In-Asia-manufactured rhG-CSF 300 mcg for prevention of CHOP (
Harryanto Reksodiputro, Zubairi Djoerban, Karmel L. Tambunan, Aru W. Sudoyo, Abidin Widjanarko, Djumhana Atmakusuma, Syafrizal Syafei, Nugroho Prayogo, Ronald Hukom, Dody Ranuhardy, Zakifman Jack, Asrul Harsal, Noorwati S, Bambang Karsono, Shufrie Effendi, Hilman Tadjoedin   +15 more
doaj   +1 more source

A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period.

PLoS ONE, 2019
For better management of patients with febrile neutropenia, our study investigated the epidemiologic, microbiologic, and clinical characteristics of adult inpatients with febrile neutropenia and their mortality-associated factors. To this end, we carried
Roberto L Parodi, Mariana Lagrutta, Mauro Tortolo, Estefanía Navall, María S Rodríguez, Gervasio F Sasia, Lucas F De Candia, Matias A Gruvman, Oscar Bottasso, Alcides A Greca   +9 more
doaj   +1 more source

Risk factors for febrile neutropenia and effectiveness of primary prophylaxis with pegfilgrastim in patients with esophageal cancer treated with docetaxel, cisplatin, and 5-fluorouracil

World Journal of Surgical Oncology, 2019
Background The docetaxel, 5-fluorouracil, and cisplatin (DCF) regimen is an effective form of chemotherapy for advanced esophageal cancer. However, the incidence of adverse events such as febrile neutropenia and hematological toxicity is high.
Yu Ohkura, Masaki Ueno, Harushi Udagawa
doaj   +1 more source

Incidence of febrile neutropenia with commonly used chemotherapy regimen in localized breast cancer

South Asian Journal of Cancer, 2020
Introduction: Breast cancer is the most frequently diagnosed cancer among the women. Most commonly used chemotherapy regimen is Doxorubicin and Cyclophosphamide (AC) which carries significant risk of febrile neutropenia.
Nageswara Reddy Palukuri, Rajani Priya Yedla, Stalin Chowdary Bala, Siva Prasad Kuruva, Rachana Chennamaneni, Meher Lakshmi Konatam, Sadashivudu Gundeti   +6 more
doaj   +1 more source

Efficacy and Safety of Filgrastim and Its Biosimilars to Prevent Febrile Neutropenia in Cancer Patients: A Prospective Study and Meta-Analysis

Biology, 2021
Background: The aim of this review and meta-analysis was to identify, assess, meta-analyze and summarize the comparative effectiveness and safety of filgrastim in head-to-head trials with placebo/no treatment, pegfilgrastim (and biosimilar filgrastim to ...
Shruti Rastogi, Vivekananda Kalaiselvan, Sher Ali, Ajaz Ahmad, Sameer Ahmad Guru, Maryam Sarwat   +5 more
doaj   +1 more source

Effect of Designing Nursing Protocol regarding Chemotherapy Induced Febrile Neutropenia: Nurses performance and Patients’ related Outcome [PDF]

Tanta Scientific Nursing Journal
Background: Febrile neutropenia  is serious complication of many chemotherapy regimen, the   Oncology nurses serve as key frontline providers in the execution of clinical protocols designed for febrile neutropenia care.
Amany Abdallah, Seham Abd El-Hay, Shimaa Farghaly, Alyaa Mohammed Elseadi   +3 more
doaj   +1 more source

Risk Adapted Management of Febrile Neutrepenia and Early Cessation of Empirical Antibiotherapy in Hematopoietic Stem Cell Transplantation Setting

Balkan Medical Journal, 2017
Background: Haematopoietic stem cell transplantation is a curative treatment option for many haematological disorders. Infection following haematopoietic stem cell transplantation is one of the major causes of mortality.
Ali Hakan Kaya, Emre Tekgündüz, Fazilet Duygu, Dicle Koca, Filiz Bekdemir, Hikmetullah Batgi, Bahar Ulu Uncu, Tuğçe Nur Yiğenoğlu, Mehmet Sinan Dal, Merih Çakar Kızıl, Fevzi Altuntaş   +10 more
doaj   +1 more source

Open-labeled, multicenter phase II study of prophylactic administration of pegylated granulocyte colony-stimulating factor in relapsed or refractory multiple myeloma who received pomalidomide-based regimens (KMM170)

Frontiers in Oncology, 2023
IntroductionPegylated granulocyte colony-stimulating factor (G-CSF) has been widely used for preventing febrile neutropenia in various types of cancer treatment. In the present study, we prospectively evaluated the safety and efficacy of pegfilgrastim as
Ga-Young Song, Je-Jung Lee, Joon Ho Moon, Dajung Kim, Min Kyoung Kim, Hyo Jung Kim, Yeung-Chul Mun, Won-Sik Lee, Young Rok Do, Jae Hoon Lee, Sung-Hoon Jung, Jin Seok Kim   +11 more
doaj   +1 more source

Multivariate analysis of febrile neutropenia occurrence in patients with non-Hodgkin lymphoma: data from the INC-EU Prospective Observational European Neutropenia Study

, 2008
Summary Myelosuppression, particularly febrile neutropenia (FN), are serious dose-limiting toxicities that occur frequently during the first cycle of chemotherapy.
Impact of Neutropenia in Chemotherapy-European Study Group (INC-, Paridaens, R, Szucs, Thomas D., Matthias Schwenkglenks, Pettengell, R, Bosly, André, Schwenkglenks, Matthias, Jackisch, C, Jackisch, Christian, Thomas D. Szucs, Manuel Constenla, Constenla, Manuel, Szucs, T D, Schwenkglenks, M, André Bosly, Leonard, Robert, Paridaens, Robert, Christian Jackisch, Robert Leonard, Pettengell, Ruth, Ruth Pettengell, Robert Paridaens, Bosly, A, Impact of Neutropenia in Chemotherapy-European Study Group,, Szucs, TD, Leonard, R, Constenla, M   +26 more
core   +1 more source

Antimicrobial de-escalation in patients with high-risk febrile neutropenia: Attitudes and practices of adult hospital care providers

Antimicrobial Stewardship & Healthcare Epidemiology, 2021
In a survey of adult hospital providers regarding antibiotic use in the treatment of febrile neutropenia, clinical fellows, and pharmacists showed higher comfort levels with early antimicrobial de-escalation compared to hematology-oncology and transplant
Chelsea A. Gorsline, Milner B. Staub, George E. Nelson, Whitney J. Nesbitt, Bhagirathbhai R. Dholaria, Gowri Satyanarayana   +5 more
doaj   +1 more source