Results 71 to 80 of about 35,270 (248)

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Chemotherapy Induced Neutropenia, Febrile-Neutropenia and Determinants Among Solid Cancer Patients Attending Oncology Unit of a Tertiary Care Teaching Hospital in Ethiopia

Cancer Management and Research, 2023
Mekonnen Dessalegn,1,2 Mengistu Fantahun,2 Abdu Adem Yesufe,2 Mintewab Hussein,1 Aster Tsegaye1 1Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2St Paul’s Hospital Millennium Medical ...
Dessalegn M, Fantahun M, Yesufe AA, Hussein M, Tsegaye A   +4 more
doaj  

A de-escalation protocol for febrile neutropenia cases and its impact on carbapenem resistance: A retrospective, quasi-experimental single-center study

Journal of Infection and Public Health, 2016
Our objective was to evaluate the impact of using an imipenem de-escalation protocol for empiric febrile neutropenia on the development of carbapenem resistance.A pre-post intervention design was used.
Abeer Alshukairi, Haleema Alserehi, Aiman El-Saed, Mouhammed Kelta, Jalil U. Rehman, Farrukh A. Khan, Hanadi Alsalmi, Majda Alattas, Muhammad Aslam   +8 more
doaj   +1 more source

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease

Internal Medicine Journal, EarlyView.
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar, Jun Yen Ng, Adam Bryant, Annmarie Bosco, Hugh C. Caterson, Pratyush Giri, Pravin Hissaria, Simon J. Harrison, Stephen Lade, Connull Leslie, Jacinta Perram, H. Miles Prince, Dejan Radeski, Maureen Rischmueller, Craig Wallington‐Gates, Nicholas Weber, Alberta Hoi   +16 more
wiley   +1 more source

Malnutrition is a predisposing factor for developing recurrent fever following febrile neutropenia in children with acute lymphoblastic leukemia

Pediatric Hematology Oncology Journal, 2020
Introduction: The factors that predict recurrence of fever following defervescence (DS) during febrile neutropenia (FN) episode have not been studied. The objective was to estimate the incidence and risk factors for recurrent fever (RF) in children with ...
Jaikumar Govindaswamy Ramamoorthy, Venkatraman Radhakrishnan, Prasanth Ganesan, Manikandan Dhanushkodi, T.S. Ganesan, T.G. Sagar   +5 more
doaj   +1 more source

Primary prophylactic colony-stimulating factors for the prevention of chemotherapy-induced febrile neutropenia in breast cancer patients [PDF]

, 2012
High-dose or dose-intensive cytotoxic chemotherapy often causes myelosuppression and severe neutropenia among cancer patients. Severe neutropenia accompanied by fever, named febrile neutropenia (FN), is the most serious manifestation of neutropenia ...
Horneber, Markus, Renner, Peter, Zwahlen, Marcel, Birkmann, Josef, Milazzo, Stefania, Liu, Jian Ping   +5 more
core   +1 more source

Mucositis: from febrile neutropenia to febrile mucositis

, 2009
© The Author 2009. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved.The treatment of patients with cancer is often accompanied by life-threatening complications caused by ...
Blijlevens, N., Netea, M., Blijlevens, N.M.A., Logan, R., Netea, M.G., Logan, A.   +5 more
core   +1 more source

How I treat febrile neutropenia

, 2021
The management of febrile neutropenia is a backbone of the treatment of patients with hematologic malignancies, and has evolved over the past decades. This article reviews my approach to the evaluation and treatment of febrile neutropenic patients.
Marcio Nucci
core   +1 more source

Alerts and Alarms—Can Electronic Medical Records Help Children and Adolescents Survive Sepsis?

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Early recognition and treatment of paediatric sepsis has been shown to improve survival. Automated sepsis alerts embedded in electronic medical records (EMRs) offer real‐time identification of high‐risk patients and may improve timeliness of sepsis care, with possible limitations including overdiagnosis, overtreatment and alert fatigue.
Ben Driver, Franz E. Babl, Daryl Cheng, Ben Gelbart, Elliot Long, Sarah McNab, Joshua Osowicki, Pauline Salib, Amanda Williams, Gabrielle M. Haeusler   +9 more
wiley   +1 more source

Management of Kaposiform Haemangioendothelioma—A Retrospective Case Series Examining the Use and Effectiveness of Vincristine

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Kaposiform haemangioendothelioma is a rare vascular tumour. Management has evolved over the last two decades, with most cases receiving vincristine or sirolimus. We aim to describe our experience with managing this tumour, with a focus on the safety and efficacy of vincristine.
Bronwen Kirk, Susan Adams, Orli Wargon, Artiene Tatian, Susan Russell   +4 more
wiley   +1 more source