Results 111 to 120 of about 367,412 (367)

Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]

, 2015
Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona, Diehl, Beate, Duncan, John S, Harper, Ronald M, Koepp, Matthias, Lhatoo, Samden, Micallef, Caroline, Sander, Josemir W, Scott, Catherine, Sisodiya, Sanjay M, Thom, Maria, Vos, Sjoerd B, Wandschneider, Britta   +12 more
core   +3 more sources

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

Epilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan, Beatrice Southby Goad, Meagan Allen, Jill Rodda, Kay L. Richards, Simone L. Ardern‐Holmes, Daniel Bamborschke, Daniel Fritzen, Inna Hughes, Kate Riney, Ana Roche Martinez, Angelo Russo, Adriane Sinclair, Stefano Sartori, Marina Trivisano, Angela De Dominicis, Nicola Specchio, Rikke S. Møller, Ingrid E. Scheffer, Walid Fazeli, Markus Wolff, Steven Petrou, Katherine B. Howell, Géza Berecki   +23 more
wiley   +1 more source

Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures

Journal of Neuroinflammation, 2011
Objective Febrile seizures are the most common form of childhood seizures. Fever is induced by pro-inflammatory cytokines during infection, and pro-inflammatory cytokines may trigger the development of febrile seizures.
Min Hyun Jin, Choi Jieun, Shin Jeon-Soo
doaj   +1 more source

Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A [PDF]

, 2017
Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and mesial temporal lobe ...
Alhusaini, Saud, Becker, Albert, Becker, Felicitas, Berkovic, Samuel F., Blumcke, Ingmar, Buchfelder, Michael, Buono, Russell J., Catarino, Claudia B., Cavalleri, Gianpiero L., Chaves, João, Coras, Roland, Costa, Paulo P., da Silva, António M., Dahl, Hans-Henrik M., de Graan, Pierre N. E., Delanty, Norman, Depondt, Chantal, Doherty, Colin P., Dorn, Thomas, Duncan, Susan, Eriksson, Kai J., Gruber-Sedlmayr, Ursula, Hakonarson, Hakon, Hallmann, Kerstin, Hamer, Hajo M., Hansen, Jörg, Hessel, Ellen V. S., Hildebrand, Michael S., Kantanen, Anne-Mari, Kasperavičiūtė, Dalia, Kobow, Katja, Koeleman, Bobby P. C., Krämer, Günter, Kunz, Wolfram S., Kälviäinen, Reetta K., Leal, Bárbara, Lerche, Holger, Leu, Costin, Matarin, Mar, Meng Tan, K., Novy, Jan, O'Brien, Terence J., Pandolfo, Massimo, Paravidino, Roberta, Petrovski, Slave, Ramasamy, Adaikalavan, Reif, Philipp S., Reinthaler, Eva M., Robbiano, Angela, Rosenow, Felix, Ryten, Mina, Rössler, Karl, Scheffer, Ingrid E., Schlachter, Kurt, Schoch, Susanne, Silva, Berta M., Sisodiya, Sanjay M., Smith, Colin, Sperling, Michael R., Steinhoff, Bernhard J., Stogmann, Elisabeth, Striano, Pasquale, Théâtre, Emilie, Tostevin, Anna, Trabzuni, Daniah, von Lehe, Marec, Weale, Michael E., Weber, Yvonne, Zara, Federico, Zimprich, Fritz, Zumsteg, Dominik   +70 more
core  

The assessment of laboratory parameters in children with fever and febrile seizures

Brain and Behavior, 2017
The aim of the research paper was to assess selected laboratory results in children with fever without seizures and febrile seizure.
Krystyna Gontko-Romanowska, Z. Żaba, Paweł Panieński, B. Steinborn, Michał Szemień, Magdalena Łukasik-Głębocka, Krystian Ratajczak, J. Górny   +7 more
semanticscholar   +1 more source

Development and validation of a deep survival model to predict time to seizure from routine electroencephalography

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate a deep survival model (EEGSurvNet) that analyzes routine electroencephalography (EEG) to predict individual seizure risk over time, comparing its performance to traditional clinical predictors such as interictal epileptiform discharges (IEDs).
Émile Lemoine, An Qi Xu, Mezen Jemel, Frédéric Lesage, Dang K. Nguyen, Elie Bou Assi   +5 more
wiley   +1 more source

The Correlation b etween IL - 1β and IL - 10 Levels in Estimating t he Risk of Febrile Seizures

Journal of Tropical Life Science, 2014
Febrile seizures are the most-common form of seizures in children with fever and evidence from clinical and experimental studies suggests the potential role of immune generated products in their genesis.
Gunawan A, Muid M, Sujuti H, Barlianto W, Subandiyah K   +4 more
doaj  

Molecular Mechanism Involved in the Pathogenesis of Early-Onset Epileptic Encephalopathy [PDF]

, 2019
Recent studies have shown that neurologic inflammation may both precipitate and sustain seizures, suggesting that inflammation may be involved not only in epileptogenesis but also in determining the drug-resistant profile.
Corsello G, Falsaperla R, Marino S, Pavone P, Saporito MAN, Vitaliti G   +5 more
core   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Characteristics of Children Admitted to the Emergency Department with Convulsive Epileptic Seizures: A Single-Center Study

Journal of Pediatric Emergency and Intensive Care Medicine, 2017
Introduction: To evaluate the etiology and characteristics of children admitted to the emergency department with an acute convulsive epileptic seizure. Methods: Data of patients who were admitted to the emergency department with a convulsive epileptic ...
Emel Ataş Berksoy, Ünsal Yılmaz, Rana İşgüder, Selçuk Yazıcı, Tanju Çelik, Aycan Ünalp   +5 more
doaj   +1 more source