Abstract Objectives 5‐Aminosalicylic acid (5‐ASA) is recommended as a first‐line medication in mild to moderate ulcerative colitis (UC), but indications regarding its use in children with moderate to severe disease treated with biologics are lacking.
Giulia D'Arcangelo +12 more
wiley +1 more source
Updated ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease 2025
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi +35 more
wiley +1 more source
Effects of Calcareous Marine Algae on Feedlot Performance, Carcass Traits, Nutrient Digestion and Enteric Methane Emissions of Feedlot-Finished Nellore Heifers. [PDF]
Fávero IG +9 more
europepmc +1 more source
Microbial communities and functional diversity in seafood
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi +3 more
wiley +1 more source
Characterizing Apixaban Pharmacokinetics Through Physiologically-Based Pharmacokinetic Modeling: Critical Role of Biliary Secretion and Enterohepatic Circulation in Humans. [PDF]
Tsuchitani T, Kou W, Tomi M, Sugiyama Y.
europepmc +1 more source
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik +6 more
wiley +1 more source
A Systematic Study of the Hepatic-Intestinal First-Pass Effect and Excretion Pathways of Punicalagin Based on UPLC-MS/MS. [PDF]
Chen Z, Chang Z, Yao P, Gao X.
europepmc +1 more source
Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
Ultrasensitive Tracking of Dual Antiparasitics in Living Tissues: UPLC-MS/MS Reveals Synergistic Distribution of Oxyclozanide and Levamisole Hydrochloride. [PDF]
Dai G +8 more
europepmc +1 more source

