Results 151 to 160 of about 244,874 (266)

The Prognostic and Functional Impact of Multimorbidity in Systemic Sclerosis

ACR Open Rheumatology, Volume 7, Issue 4, April 2025.
Objective Our objective was to define the frequency and impact of multimorbidity in systemic sclerosis (SSc). Method Australian Scleroderma Cohort Study participants meeting American College of Rheumatology/EULAR criteria were included. Charlson Comorbidity Index scores were calculated at each visit, with multimorbidity defined as scores ≥4 ...
Jessica L. Fairley, Dylan Hansen, Susanna Proudman, Joanne Sahhar, Gene‐Siew Ngian, Diane Apostolopoulos, Jennifer Walker, Lauren V. Host, Wendy Stevens, Mandana Nikpour, Laura Ross   +10 more
wiley   +1 more source

Controversies in fecal incontinence. [PDF]

World J Gastroenterol
Albuquerque A, Rao SSC.
europepmc   +1 more source

An Intervertebral Disc (IVD) Regeneration Model Using Human Nucleus Pulposus Cells (iHNPCs) and Annulus Fibrosus Cells (iHAFCs)

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
This study investigates hTert‐immortalized human nucleus pulposus (iHNPCs) and annulus fibrosus (iHAFCs) cells for intervertebral disc (IVD) regeneration and spinal fusion models. A 3D‐printed citrate‐based scaffold loaded with BMP9‐stimulated iHAFCs and BMP2‐stimulated iHNPCs effectively promotes bone and cartilage formation, mimicking the IVD ...
Yi Zhu, Qing Liu, Chao Yu, Hui Zhang, Jiamin Zhong, Yonghui Wang, Ou Mei, Ethan Gerhard, Wulin You, Guowei Shen, Changqi Luo, Xingye Wu, Jingjing Li, Yi Shu, Ya Wen, Usman Zeb, Hue H. Luu, Michael J. Lee, Lewis L. Shi, Yang Bi, Jian Yang, Jiaming Fan, Russell R. Reid, Tong‐Chuan He, Liangyuan Wen   +24 more
wiley   +1 more source

Anorectal Friction Force Is Reduced in Fecal Incontinence. [PDF]

Gastro Hep Adv
Gregersen H, Patel B, Guo X, Barron Del Solar G, Eisenstein S, Kassab G.   +5 more
europepmc   +1 more source

Discover the Power of Lithospermic Acid as Human Carbonic Anhydrase VA and Pancreatic Lipase Inhibitor Through In Silico and In Vitro Studies

Archiv der Pharmazie, Volume 358, Issue 4, April 2025.
Aiming at safe obesity drugs, Salvia miltiorrhiza was explored, and lithospermic acid was identified as a dual inhibitor of pancreatic lipase and human carbonic anhydrase VA. In silico and experimental analyses revealed stable binding interactions and good inhibitory effects.
Emanuele Liborio Citriniti, Roberta Rocca, Giosuè Costa, Claudia Sciacca, Nunzio Cardullo, Vera Muccilli, Anastasia Karioti, Fabrizio Carta, Claudiu T. Supuran, Stefano Alcaro, Francesco Ortuso   +10 more
wiley   +1 more source

Disseminated Neurocysticercosis With Intraventricular and Cisternal Extension Without Hydrocephalus: A Case Report

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Neurocysticercosis, a leading cause of acquired epilepsy, can present as disseminated disease with widespread cystic lesions. A 33‐year‐old male with seizures and weakness showed radiologically confirmed neurocysticercosis. Treatment with steroids, antiparasitics, and antiseizure medication led to improvement. Early diagnosis and public health
Bibek Shrestha, Priyesh Shrestha, Bikram Prasad Gajurel, Grishma Kandel, Laxmi Shah   +4 more
wiley   +1 more source

Clinical characteristics of phenotypes of fecal incontinence. [PDF]

Tech Coloproctol, 2023
Knol ME, Bastiaannet E, DeRuiter MC, Snijders HS, van der Heyden JTM, Baeten CIM.   +5 more
europepmc   +1 more source

Biofeedback Therapy in Managing Functional Fecal Incontinence in Children: A Literature Review. [PDF]

Cureus
Caldas Afonso S, Caria Ramalhao N, Cavalheiro A, Trepa A.   +3 more
europepmc   +1 more source

Long-term outcome after SphinKeeper® surgery for treating fecal incontinence-who are good candidates? [PDF]

Langenbecks Arch Surg, 2023
Dawoud C, Widmann KM, Pereyra D, Harpain F, Riss S.   +4 more
europepmc   +1 more source

A rectal ulcer caused by hydrogel spacer insertion: A case report and review of the literature

DEN Open, Volume 5, Issue 1, April 2025.
Abstract A 75‐year‐old man presented with hematochezia. He had been diagnosed with prostate cancer (stage 1) 1 month previously and had undergone gold marker injection and hydrogel spacer insertion 3 weeks previously to prepare for radiotherapy. Hydrogel spacer insertion is a safe procedure that can prevent the side effects of radiotherapy for prostate
Sen Yagi, Moyu Kawano, Keitaro Kawasaki, Takatoshi Murakami, Jiro Miyaike, Shinya Furukawa   +5 more
wiley   +1 more source