Results 31 to 40 of about 3,348,595 (338)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Exploring the Federal Role in Protecting Canada’s Farmland: A Matter Worthy of National Interest?

open access: yesCanadian Planning and Policy, 2020
Is protecting farmland a matter of national interest? If so, should the federal government play a stronger role in agricultural land use planning (AgLUP)?
David J. Connell
doaj   +1 more source

¿Qué territorio para cuál nación? Soberanías territoriales y rivalidades interprovinciales en el Río de la Plata (1820-1840)

open access: yesNuevo mundo - Mundos Nuevos, 2019
This article deals with the territorial aspects of the fragmentation of sovereignty and analyzes the different territorial configurations resulting from the dismantling of imperial structures in the Rio de la Plata, in order to call into question the ...
Geneviève Verdo
doaj   +1 more source

Elections, Ideology, and Turnover in the U.S. Federal Government

open access: yesJournal of public administration research and theory, 2016
A defining feature of public sector employment in the United States is the regular change in elected leadership. We describe how these changes alter policy and disrupt civil servants’ influence over agency decisions, potentially shaping their career ...
Alexander Bolton   +2 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

AVALIAÇÃO DO IMPACTO REGULATÓRIO E SUA DIFUSÃO NO CONTEXTO BRASILEIRO [PDF]

open access: yesRAE: Revista de Administração de Empresas, 2011
Regulatory Impact Assessment (RIA) is one of the instruments aiming regulatory quality improvement. Research has shown limitationsin RIA diffusion process, particularly in developing countries, due to political forces at work in domestic contexts or to ...
Alketa Peci
doaj  

The Comparative Analysis of the Legal Bases Regulating the Principles of the Organization of Local Government in the Russian Federation, Provided By the Federal Law of 28.08.1995 N 154-FZ and the Federal Law of 06.10.2003 N 131-FZ

open access: yesУправленческое консультирование, 2019
The article is devoted to research of the legal bases regulating the principles of the organization of local government in the Russian Federation, provided by the Federal law of 28.08.1995 N 154-FZ and the Federal law of 06.10.2003 N 131-FZ.
Yu. V. Vasilyeva
doaj   +1 more source

Expenditures and Revenues of the Federal Government [PDF]

open access: yesThe ANNALS of the American Academy of Political and Social Science, 1921
n ...
openaire   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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