Results 31 to 40 of about 6,876,174 (307)

Breathing fresh air into the debate: Ventilators and the United States' intellectual property problem

open access: yesHealth Policy Open, 2022
In 2006, the U.S. federal government launched a project to create a cheap, easily produced, and easy to use ventilator that could be stored for long periods of time for pandemic response. Despite successful funding and contracts with two separate medical
Theora W. Tiffney   +2 more
doaj   +1 more source

Federal Government Memorabilia - Accession 1485 - M727 (783)

open access: yes, 2020
This series consists of four War Department Field Manuals titled: Basic Field Manual: Field Service Pocketbook Sketching (FM 21-35) (1939); Elementary map and Aerial Photograph Reading (FM 21-25) (August 15, 1944); Aerial Photography Military ...
Federal Government
core   +1 more source

Federal government views on the report of the tribunal of inquiry on the University of Ife students accident [PDF]

open access: yes, 1982
this is federal government views on the report of the tribunal of inquiry on the University of Ife students accidentAs a result of the incident which led to the death of some students of the University of Ife on 7th June, 1981, the President of the ...
FEDERAL Government of Nigeria
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Government view on the report of the fact finding panel into the activities of civil aviation department of the federal ministry of aviation [PDF]

open access: yes, 1981
this is the report of the fact finding panel into the activities of civil aviation department of the federal ministry of aviationDepartment of civil aviation; Nigerian Airport Authority; Nigerian Civil Aviation Training Centre, Zaria; Nigerian Airway ...
FEDERAL Government of Nigeria
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Arizona Border Region: Federal Agencies Could Better Utilize Law Enforcement Resources in Support of Wildland Fire Management Activities [PDF]

open access: yes, 2011
A letter report issued by the Government Accountability Office with an abstract that begins "Wildland fires can result from both natural and human causes.
United States Government Accountability Office   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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