Results 31 to 40 of about 615,594 (260)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The European idea in Central Europe and Scandinavia as a part of the security and peaceful co-existence policy in the framework of the postwar planning [PDF]
Baltic Region, 2011 This article is dedicated to the development of European unity in Central Europe and Scandinavia as a mechanism of collective security and intergovernmental cooperation development.
Chernyshev Yevgeny
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
OSMANLI ELİTLERİNİN 1911 ALMANYA ARAŞTIRMA GEZİSİ
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2017 II. Meşrutiyet’in ilanı sonrasında ve Sultan II. Abdülhamid’in tahttan indirilmesi ile birlikte Alman İmparatorluğu, Osmanlı toplumunun ve devlet bürokrasisinin yeni temsilcileri olan Jöntürk kadroları ile ilişkiler tesis etme çabası içerisine girdi ...
Salih Kış
doaj
Information Asymmetry in Federations [PDF]
Prostranstvennaâ Èkonomika, 2014 The paper investigates the problems of information transmission between levels of government in a federal state. The central government in a federation typically faces serious difficulties while collecting information on economic and political situation ...
Alexander Mikhailovich Libman
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Institutional Factors Hindering the Development of Russian Federalism [PDF]
Prostranstvennaâ Èkonomika, 2007 Basic models of federalism, peculiarities of establishing and developing federal relations in Russia are considered. A system of institutional factors hindering the development of federalism in Russia is determined.
Sergey Dmitrievich Valentey
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The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
ANARCHIST TEACHING M. A. BAKUNIN AND MODERNITY (TO THE 210TH ANNIVERSARY OF THE THINKER’S BIRTH) [PDF]
Legal BulletinThe relevance of the ar ticle is determined by the presence in the modern world of social problems and contradictions, including in the system of international relations, which are in many ways similar to those that existed in the second half of the 19th
IVANNIKOV I.A.
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