Results 41 to 50 of about 26,852 (242)

American Primary Care Physicians’ Decisions to Leave Their Practice

Journal of Primary Care & Community Health, 2012
The status of the primary care workforce is a major health policy concern. It is affected not only by the specialty choices of young physicians but also by decisions of physicians to leave their practices.
Bradford H. Gray, Karen Stockley, Stephen Zuckerman   +2 more
doaj   +1 more source

Diagnosed prevalence of Alzheimer's disease and related dementias in Medicare Advantage plans

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Introduction One‐third of Medicare beneficiaries are enrolled in Medicare Advantage (MA). Yet, little is known about MA beneficiaries diagnosed with Alzheimer's disease (AD) and AD‐related dementias (AD/ADRD).
Eric Jutkowitz, Julie P.W. Bynum, Susan L. Mitchell, Noelle M. Cocoros, Oren Shapira, Kevin Haynes, Vinit P. Nair, Cheryl N. McMahill‐Walraven, Richard Platt, Ellen P. McCarthy   +9 more
doaj   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

British Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright, Irene Rizzini, Malibongwe Gwele, Lynn McNair, Cristina Laclette Porto, Marsha Orgill, E. Kay M. Tisdall, Malcolm Bush, Linda Biersteker   +8 more
wiley   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Directional Regulation of Zinc Deposition Through Constructing Hierarchical Janus Carbon Matrix with Organic‐Decorated Multi‐Channels

Advanced Science, EarlyView.
A Janus carbon matrix is engineered by covalently anchoring organic sulfonic anions within tubular pores of hierarchical CMK‐5, serving as an interfacial layer for Zn metal anodes. This design establishes a charge gradient for Zn2+ diffusion, enabling the directional deposition of confined and uniform Zn inside the pores while suppressing parasitic ...
Li Gao, Hongli Chen, Dongfang Li, Chen Qian, Chao Yuan, Bin Yu, Jitraporn Vongsvivut, Bernt Johannessen, Lingfei Zhao, Yaojie Lei, Hong Gao, Yufei Zhao, Jinqiang Zhang, Guoxiu Wang, Hao Liu   +14 more
wiley   +1 more source

Scalable Electrochemical Concrete Fabrication and Closed‐Loop Recycling

Advanced Science, EarlyView.
The electrochemical‐driven recycling strategy establishes a reversible concrete material flow by extracting Ca, Si, Al, and Fe from concrete waste and regenerating functional feedstocks. These reversed products are reassembled into new concrete, which re‐enters service and ultimately returns to waste, enabling a closed‐loop, waste‐origin, and low ...
Hanxiong Lyu, Zhenlin Li, Yang Liu, Lu Zhu, Lucen Hao, Mingxin Shi, Shipeng Zhang, Chi Sun Poon   +7 more
wiley   +1 more source

Quality-Based Payment for Medical Groups and Individual Physicians

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2009
This paper measures the extent to which medical groups experience external pay-for-performance incentives based on quality and patient satisfaction and the extent to which these groups pay their primary care and specialist physicians using similar ...
James C. Robinson, Stephen M. Shortell, Diane R. Rittenhouse, Sara Fernandes-Taylor, Robin R. Gillies, Lawrence P. Casalino   +5 more
doaj   +1 more source

Determinants of local food producer participation in state‐sponsored marketing programs: Evidence from Missouri

Agribusiness, EarlyView.
Abstract This study examines producer participation choices considering a variety of potential benefits linked to state‐sponsored marketing programs, using a real choice dataset of farmers in Missouri. Multinomial logit models are employed to predict determinants of farmer enrollment in three tiers of the Missouri Grown local food marketing program ...
Lan Tran, Ye Su, Laura McCann
wiley   +1 more source