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A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

Feed cost efficiency in robotic milking systems: an analysis of revenue minus feed cost across dairy cow groups in southern Brazil. [PDF]

Trop Anim Health Prod
Andelieri CB, Vilanova MS, Rezende AL, Cavallini D, Buonaiuto G, Bordin T.   +5 more
europepmc   +1 more source

Machine Learning in Mammals' Health: Integrating Multi-Omics Data for Precision Nutrition and Sustainable Production. [PDF]

Vet Sci
Huang W, Yu X, Xia Y, Li W, Zhao X.
europepmc   +1 more source

From Invasive Bramble to Functional Browse: A Translational Review of <i>Rubus ulmifolius</i> Schott for Sheep Nutrition. [PDF]

Plants (Basel)
Cancino-Baier D, Quiñones-Diaz J, Diaz R, Muñoz-Acuña E, Becker NS, Paz EA, Muñoz-Salvo A.   +6 more
europepmc   +1 more source

Machine Learning-Driven Design of Experiments for CO₂ Mineralization of Steel Slag Materials. [PDF]

ACS Omega
Radfarnia H, Samputu I, Zanganeh K.
europepmc   +1 more source

Integrated Biorefineries for Food Waste and Food-Processing Side Streams Through Feedstock-Oriented Design and Sustainable Process Integration. [PDF]

Foods
Lazăr Coșbuc ED, Oprea Blanaru PS, Ungureanu-Comăniță ED, Teodosiu C, Gavrilescu M.   +4 more
europepmc   +1 more source

Antioxidant, Anti-Inflammatory, and Immunomodulatory Benefits of DDGS in Broiler Growth and Meat Quality. [PDF]

Vet Med Int
Salah AS, Taha AE, Hassan RIM, Mohamed EM, Elkareem AHA, Saaty AH, Alagawany M, Islam KMS, Amer HY.   +8 more
europepmc   +1 more source

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Cost Optimization of Feed Mixes by Genetic Algorithms

Advances in Engineering Software, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mehmet Çunkaş, Şeref Inal
exaly   +3 more sources