Results 31 to 40 of about 126,662 (218)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Opioid System and Leucine Interaction in the Regulation of Feed Intake in Broiler Chickens [PDF]

Veterinary and Comparative Biomedical Research
The opioidergic system plays a critical role in feed intake, among other physiological functions. This study investigated the potential effects of the opioidergic system, leucine and its interaction with the central regulation of feed intake in broilers.
Seyyed Sattar Tohidifar, Javad Cheraghi, Amirali Ebrahimi Jamal, Morteza Zendehdel, Jahangir Kaboutari   +4 more
doaj   +1 more source

A procedure to quantify the feed intake response of growing pigs to perturbations

Animal, 2020
Improving robustness of farm animals is one of the goals in breeding programmes. However, robustness is a complex trait and not measurable directly. The objective of this study was to quantify and characterize (elements of) robustness in growing pigs ...
H. Nguyen-Ba, J. van Milgen, M. Taghipoor   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Genomic Regions Associated with Feed Efficiency Indicator Traits in an Experimental Nellore Cattle Population. [PDF]

PLoS ONE, 2016
The objective of this study was to identify genomic regions and metabolic pathways associated with dry matter intake, average daily gain, feed efficiency and residual feed intake in an experimental Nellore cattle population.
Bianca Ferreira Olivieri, Maria Eugênia Zerlotti Mercadante, Joslaine Noely Dos Santos Gonçalves Cyrillo, Renata Helena Branco, Sarah Figueiredo Martins Bonilha, Lucia Galvão de Albuquerque, Rafael Medeiros de Oliveira Silva, Fernando Baldi   +7 more
doaj   +1 more source

Nutrient intake of captive small Indian civet (Viverricula indica) in Chiang Mai Zoo and Demonstrated Farming Under Royal Project in Ban Dong Yen, Thailand

Veterinary Integrative Sciences, 2023
Here we examined the feed and nutrient intake of captive small Indian civets (Viverricula indica) housed at the Chiang Mai Zoo (CMZ) and Demonstrated Farming Under Royal Project (DYF) in Ban Dong Yen in Thailand.
Theerapong Nakas, Phichit Chitmin, Ratchaneewan Punyatong, Runglawan Sangsuri, Sasiwimon Jatoorapattarawong, Pattaranun Whongchai, Tharathep Phopheng, Pradit Wonglungkar, Watcharaphong Kittichroenwit, Montri Punyatong   +9 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Feed intake in Atlantic salmon fed with or without surface spreading of feed

Journal of Agricultural and Marine Sciences, 2020
In intensive salmon farming, it is common practice to spread the feed over a large surface area, assuming that spreading of the feed increases feed intake in the fish.
Turid Synnøve Aas, Trine Ytrestøyl, Torbjørn Åsgård, Kristoffer Rist Skøien, Morten Omholt Alver, Jo Arve Alfredsen   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source