Results 91 to 100 of about 11,747,428 (292)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Stabilizing a nonlinear system by using feedback control [PDF]
, 2010 This dissertation considers how to stabilize a nonlinear system by using feedback control. To stabilize a nonlinear system, we first need to find the unstable steady state.
Kareem, Rasaq
core +2 more sources
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Feedback Control of Spin Systems [PDF]
Quantum Information Processing, 2006 The feedback stabilization problem for ensembles of coupled spin 1/2 systems is discussed from a control theoretic perspective. The noninvasive nature of the bulk measurement allows for a fully unitary and deterministic closed loop. The Lyapunov-based feedback design presented does not require spins that are selectively addressable.
openaire +2 more sources
Adaptive control for double-integrator class systems in the absence of velocity feedback [PDF]
, 2013 textThis work considers formulation of new classes of adaptive controllers for double-integrator type systems where the underlying system parameters are uncertain and the complete state-vector is not available for feedback.
Yang, Sungpil
core
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
The Feedback Trombone: Controlling Feedback In Brass Instruments
, 2018 This paper presents research on control of electronic signal feedback in brass instruments through the development of a new augmented musical instrument, the Feedback Trombone. The Feedback Trombone (FBT) extends the traditional acoustic trombone interface with a speaker, microphone, and custom analog and digital hardware.
Jeff Snyder +2 more
openaire +3 more sources
A Result on Output Feedback Linear Quadratic Control [PDF]
In this note we consider the static output feedback linear quadratic control problem.We present both necessary and sufficient conditions under which this problem has a solution in case the involved cost depend only on the output and control variables ...
Weeren, A.J.T.M., Engwerda, J.C.
core