Results 81 to 90 of about 11,747,428 (292)

Rocking feedback-controlled ratchets

open access: yesPhysical Review E, 2009
LaTeX, 8 pages, 8 figures. To appear in Phys.
Feito, M.   +2 more
openaire   +6 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

A Control Theory Approach to Understanding the Dynamics of Cognitive Wellbeing

open access: yesSocial Sciences
(1) Background and Objective: The debate on the stability and variability of subjective wellbeing (SWB) is decades old. However, despite the wealth of literature on this topic, there are relatively few studies that aim to explain the “why” and “how” of ...
Ioan Susnea   +5 more
doaj   +1 more source

A Preliminary Prototype High-Speed Feedback Control of an Artificial Cochlear Sensory Epithelium Mimicking Function of Outer Hair Cells

open access: yesMicromachines, 2020
A novel feedback control technique for the local oscillation amplitude in an artificial cochlear sensory epithelium that mimics the functions of the outer hair cells in the cochlea is successfully developed and can be implemented with a control time on ...
Hiroki Yamazaki   +2 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Controlling Cell Migratory Patterns Under an Electric Field Regulated by a Neural Network-Based Feedback Controller

open access: yesBioengineering
Electric fields (EFs) are widely employed to promote tissue regeneration and accelerate wound healing. Despite extensive study, the cellular responses elicited by EFs are complex and not well understood.
Giovanny Marquez   +11 more
doaj   +1 more source

Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy

open access: yesMolecular Systems Biology, 2007
Robust biological signaling networks evolved, through gene duplications, from simple, relatively fragile cascades. Architectural features such as layered configuration, branching and modularity, as well as functional characteristics (e.g., feedback ...
Ido Amit, Ron Wides, Yosef Yarden
doaj   +1 more source

Long-pulse H-mode operation with stored-energy monitoring for detachment feedback control with a new lower tungsten divertor in EAST

open access: yesNuclear Fusion, 2023
One of the key challenges for future fusion research is to mitigate the high steady-state heat load on the divertor target plates, and divertor detachment offers a promising solution. The Experimental Advanced Superconducting Tokamak (EAST) has developed
Y.Q. Tao   +24 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

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