Results 81 to 90 of about 1,016,114 (310)
A Control Theory Approach to Understanding the Dynamics of Cognitive Wellbeing
Social Sciences(1) Background and Objective: The debate on the stability and variability of subjective wellbeing (SWB) is decades old. However, despite the wealth of literature on this topic, there are relatively few studies that aim to explain the “why” and “how” of ...
Ioan Susnea +5 more
doaj +1 more source
Monolithically Integrated Light Feedback Control Circuit for Blue/UV LED Smart Package
IEEE Photonics Journal, 2017 Given the performance decay of high-power light-emitting diode (LED) chips over time and package condition changes, having a reliable output light for sensitive applications is a point of concern.
Zahra Kolahdouz Esfahani +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
New results in feedback control of unsupported standing in paraplegia [PDF]
, 2004 The aim of this study was to implement a new approach to feedback control of unsupported standing and to evaluate it in tests with an intact and a paraplegic subject.
Hunt, K.J., Gollee, H., Wood, D.E.
core
A design approach for feedback-feedforward control systems
, 2010 In this paper, a general design approach based on the concept of ‘Control Equilibrium Point’ is proposed to derive the feedforward control law in feedback-feedforward control systems.
Mohammadzaheri, M. +3 more
core +1 more source
Robust repetitive feedback control of a three-phase grid connected inverter [PDF]
, 2010 This paper discusses the design of a repetitive feedback controller for a grid-connected two-level three-phase voltagesource inverter connected between a DC source and the grid through an LCL filter.
Sharkh, S.M. +8 more
core +1 more source