Results 101 to 110 of about 5,972,941 (286)

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

open access: yesAdvanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu   +12 more
wiley   +1 more source

Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici   +4 more
wiley   +1 more source

Manifesto for medical research [PDF]

open access: yes, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao   +15 more
wiley   +1 more source

Can Chemoradiotherapy Expand Immune Checkpoint Blockade Responsiveness in Mismatch Repair‐Proficient Rectal Cancer?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Immune checkpoint blockade (ICB) has transformed the treatment of mismatch repair‐deficient (dMMR) colorectal cancer but produces no meaningful benefit in advanced mismatch repair‐proficient (pMMR) disease. In the neoadjuvant setting, however, pathological responses have been reported in a subset of pMMR tumors, suggesting that clinical ...
Kimihiro Yamashita   +4 more
wiley   +1 more source

Comparison of Nationwide Volumes for Five Major Gastrointestinal Surgical Procedures in Japan: Implications From Publicly Available NCD and NDB Open Data

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim In Japan, the National Clinical Database (NCD), a clinician‐reported registry, and the National Database of Health Insurance Claims and Specific Health Checkups of Japan Open Data (NDB Open Data), an administrative claims database, are both widely used as nationwide surgical databases, but their consistency in capturing national surgical ...
Atomu Kiriyama   +3 more
wiley   +1 more source

Twelfth annual announcement and catalogue of the Woman's Medical College of Chicago 337-9 S. Lincoln Street, opposite New County Hospital. Session of 1881-1882.

open access: yes, 1881
An annual announcement from the Woman's Medical College of Chicago, which would later become Northwester University's Woman's Medical School, which discusses the curriculum, including requirements for admission and graduation, textbooks, and fees.

core  

Analysis of influencing factors on patient satisfaction in the dermatology outpatient department of a tertiary public hospital

open access: yesPifu-xingbing zhenliaoxue zazhi
Objective To analyze outpatient experience satisfaction and its influencing factors among dermatology patients at a tertiary public hospital, and to improve dermatologists'understanding of patients'needs while enhancing the overall quality of medical ...
GAO Yan   +4 more
doaj   +1 more source

Modular design and supervisory control for enhanced economic resilience in continuous pharmaceutical manufacturing

open access: yesAIChE Journal, EarlyView.
Abstract Conventional continuous plants use fixed‐capacity equipment, resulting in high capital risk and suboptimal performance under fluctuating demands. To address these, this study proposes an integrated framework for modular process design and supervisory control capable of adapting to demand uncertainty for long‐term economic viability.
T. Asrav, M. Alvarado‐Morales, G. Sin
wiley   +1 more source

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