Results 31 to 40 of about 801,899 (276)

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez   +13 more
wiley   +1 more source

General practitioners' willingness to pay for continuing medical education in a fee-for-service universal coverage health care system [article] [PDF]

open access: yes, 2014
: Background: Sponsoring of medical meetings by life science companies has led to reduced participation fees for physicians but questions potential drawbacks. Ongoing discussions are proposing to ban such sponsoring which may increase participation fees.
Auer, R.   +4 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Parental perspectives on surgical fees of pediatric squint surgeries

open access: yesJournal of Clinical Ophthalmology and Research, 2014
Aim: To report the parental feedback on the ′squint surgery fees′ of their ward in an urban private practice. Design: Prospective cohort study. Subjects and Methods: Three months after the surgery, a 10 item questionnaire was administered on the parents ...
Mihir Kothari, Sheetal Baldua
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Integrated Information System Smart E:Hospital the Innovation and Improvement of the Services and Management Hospital

open access: yesLontar Komputer, 2023
The use of technology can transform conventional systems into electronic-based systems. Electronic systems have been widely used in governance, organizations, and companies where administration is carried out electronically (e-Government).
Oka Sudana   +3 more
doaj   +1 more source

Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]

open access: yes, 2019
BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida   +16 more
core   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Dying to pay: end-of-life medical costs for middle-aged and older adult patients with cardiovascular and cerebrovascular diseases

open access: yesFrontiers in Public Health
ObjectiveThis study aims to investigate end-of-life healthcare expenditures among middle-aged and older patients with cardiovascular and cerebrovascular diseases, with a particular focus on the existence of the “nearing-death effect.”MethodsUsing ...
Guoheng Hu   +3 more
doaj   +1 more source

The Impact of Inflation on the Medical and Hospital Money Transfers of the Neurosurgical Procedures of the Brazilian Unified Healthcare System from 2008 to 2017

open access: yesBrazilian Neurosurgery, 2018
Introduction There are more than 1,500 hospital procedures included in the Brazilian Unified Healthcare System's (SUS, in the Portuguese acronym) table, which is the reference for service payment provided by establishments serving the public health ...
Marcelo José Silva de Magalhães   +9 more
doaj   +1 more source

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