Results 141 to 150 of about 363,775 (271)

Feline coronavirus-associated myocarditis in a domestic longhair cat

Journal of Feline Medicine and Surgery Open Reports, 2019
Case summary A 9-month-old entire male domestic longhair indoor cat presented with a 3-week history of fluctuating fever, weight loss and small intestine diarrhoea, which was unresponsive to antibiotics and supportive treatment.
Maria A Ernandes, Anna M Cantoni, Federico Armando, Attilio Corradi, Lorenzo Ressel, Alice Tamborini   +5 more
doaj   +1 more source

An isolated epizootic of hemorrhagic-like fever in cats caused by a novel and highly virulent strain of feline calicivirus. [PDF]

, 2000
An isolated epizootic of a highly fatal feline calicivirus (FCV) infection, manifested in its severest form by a systemic hemorrhagic-like fever, occurred over a 1-month period among six cats owned by two different employees and a client of a private ...
Elliott, JB, Glasgow, A, Keel, K, Pedersen, NC, Poland, A   +4 more
core   +1 more source

Structure‐Based Rational Design of a Selective Hydrolase Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus‐2 Nsp3 Macrodomain

ChemBioChem, Volume 26, Issue 23, November 27, 2025.
Structure‐guided design of a sulfamoyl‐modified analog of GS‐441524 yielded a selective, high‐affinity inhibitor of the SARS‐CoV‐2 macrodomain Nsp3b. The compound occupies the phosphate‐binding pocket, forming a stabilizing hydrogen‐bond network that enhances binding affinity (K_D = 0.86 μM).
Robin Krishnathas, Konstantin S. Mineev, Nikolaos K. Fourkiotis, Franck Touret, Christos Sideras‐Bisdekis, Aikaterini C. Tsika, Santosh Lakshmi Gande, Verena Linhard, Sridhar Sreeramulu, Frank Lennartz, Manfred S. Weiss, Bruno Coutard, Georgios A. Spyroulias, Harald Schwalbe   +13 more
wiley   +1 more source

Feline Coronavirus and Alpha-Herpesvirus Infections: Innate Immune Response and Immune Escape Mechanisms [PDF]

, 2021
Paolo Capozza, Annamaria Pratelli, Michele Camero, Gianvito Lanave, Grazia Greco, Francesco Pellegrini, Maria Tempesta   +6 more
openalex   +1 more source

Exploring Nirmatrelvir Derivatives Through P2 Substituent Modifications and Warhead Innovations Targeting the Main Protease of SARS‐CoV‐2

Archiv der Pharmazie, Volume 358, Issue 11, November 2025.
This study explores structural tuning of SARS‐CoV‐2 Mpro inhibitors through P2 position substitutions and novel warheads. Combining computational modeling and biochemical assays, we found that hydrophobic π‐rich groups and uncommon warheads like fluoro‐vinylsulfone or nitrile enhance potency.
Felipe Cardoso Prado Martins, Johannes Lang, Fernanda dos Reis Rocho, Xianxian Wang, Vinícius Bonatto, Jerônimo Lameira, Christian Klein, Carlos Alberto Montanari   +7 more
wiley   +1 more source

Genetic Characteristics and Research Progress of Feline Coronavirus

Shiyan dongwu yu bijiao yixue
Feline coronavirus (FCoV) is classified into two biotypes: feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV). FIPV and FECV might evolve and mutate via genetic recombination and mutation, leading to novel subtypes and ...
TAO Lingyun
doaj   +1 more source

Acute onset neurological deficits and hypocalcaemia associated with nutritional secondary hyperparathyroidism in three juvenile servals (Leptailurus serval)

Australian Veterinary Journal, Volume 103, Issue 11, Page 767-774, November 2025.
Nutritional secondary hyperparathyroidism is a metabolic disorder caused by an imbalance in calcium homeostasis and is typically associated with the feeding of a calcium‐deficient diet. Nutritional secondary hyperparathyroidism has been reported in domestic species, including cats and dogs, as well as captive carnivores and wildlife including lions ...
JL Austen, JW Wheelahan, J O'Dwyer, S Beths, NL Rourke, BR Gardner   +5 more
wiley   +1 more source

SARS-CoV-2 in Quarantined Domestic Cats from COVID-19 Households or Close Contacts, Hong Kong, China

Emerging Infectious Diseases, 2020
We tested 50 cats from coronavirus disease households or close contacts in Hong Kong, China, for severe acute respiratory syndrome coronavirus 2 RNA in respiratory and fecal samples.
Vanessa R. Barrs, Malik Peiris, Karina W.S. Tam, Pierra Y.T. Law, Christopher J. Brackman, Esther M.W. To, Veronica Y.T. Yu, Daniel K.W. Chu, Ranawaka A.P.M. Perera, Thomas H.C. Sit   +9 more
doaj   +1 more source

Follow-up monitoring in a cat with leishmaniosis and coinfections with Hepatozoon felis and ‘Candidatus Mycoplasma haemominutum’ [PDF]

, 2017
Case summary A 6-year-old female neutered domestic shorthair cat from Cyprus was presented with multiple ulcerated skin nodules. Cytology and histopathology of the lesions revealed granulomatous dermatitis with intracytoplasmic organisms, consistent ...
Attipa, C, Baneth, G, Brooks-Brownlie, H, Martínez-Orellana, P, Nachum-Biala, Y, Neofytou, K, Solano-Gallego, L, Tasker, S, Yiapanis, C   +8 more
core   +6 more sources

Treatment With Remdesivir Alone or in Combination With GS‐441524 in Cats With Ocular Involvement of Feline Infectious Peritonitis: An Observational Case Series

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
ABSTRACT Background Remdesivir and GS‐441524 have successfully treated cats with feline infectious peritonitis (FIP) but the changes in associated signs of ocular disease are not reported. Objective Evaluate the response of FIP‐associated signs of ocular disease before and after treatment with remdesivir, GS‐441524, or both.
Amy L. M. M. Andrews, Eneko Izaguirre, Jodie Green, Emma Scurrell, Savina Gogova, Sarah Tayler, Christiane Kafarnik   +6 more
wiley   +1 more source