Results 181 to 190 of about 24,006 (211)

Culture of feline corneal epithelial cells and infection with feline herpesvirus-1 as an investigative tool

American Journal of Veterinary Research, 2005
Abstract Objective—To isolate and characterize pure cultures of feline corneal epithelial cells and to assess the extent and nature of feline herpesvirus (FHV)-1 infection in these cells. Sample Population—Healthy eyes from 23 recently euthanatized cats.
Lynne S, Sandmeyer, Charlotte B, Keller, Dorothee, Bienzle   +2 more
openaire   +2 more sources

Use of serologic tests to predict resistance to feline herpesvirus 1, feline calicivirus, and feline parvovirus infection in cats

Journal of the American Veterinary Medical Association, 2002
Abstract Objective—To determine whether detection of virusspecific serum antibodies correlates with resistance to challenge with virulent feline herpesvirus 1 (FHV-1), feline calicivirus (FCV), and feline parvovirus (FPV) in cats and to determine percentages of client-owned cats with serum antibodies to FHV-1, FCV, and FPV.
Michael R, Lappin, Janet, Andrews, Dan, Simpson, Wayne A, Jensen   +3 more
openaire   +2 more sources

Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase

Archives of Virology, 2007
Feline herpesvirus-1 (FHV-1) causes a severe upper respiratory and ocular disease in cats. An effective antiviral compound is required for treating FHV-1 infections. The virus-encoded thymidine kinase (TK) is the molecular basis for selective activation of commonly used antiviral nucleoside analogue drugs, e.g.
Islam T M, Hussein, Ricardo Núñez, Miguel, Laurence S, Tiley, Hugh J, Field   +3 more
openaire   +2 more sources

Clinical refresher Feline herpesvirus - 1 keratitis

Companion Animal, 2007
Recrudescent infection An estimated 80% of these infected animals become latently affected, with the virus present in the trigeminal ganglion life-long. All signs may resolve and the cat may remain asymptomatic for life. However in approximately half of these latently affected cats, the virus may become reactivated later in life. In many of these cases,
openaire   +1 more source

Survival of equine herpesvirus‐4, feline herpesvirus‐1, and feline calicivirus in multidose ophthalmic solutions

Veterinary Ophthalmology, 2002
AbstractObjectiveTo determine survival over time of infectious equine herpesvirus‐4, feline herpesvirus‐1, and feline calicivirus in three commercially available and commonly used ophthalmic solutions (eyewash, fluorescein, and proparacaine HCl).Sample populationViruses used in this study were originally isolated from eyes of animals referred to the ...
Eric S, Storey, Paul A, Gerding, Gail, Scherba, David J, Schaeffer   +3 more
openaire   +2 more sources

Detection of feline herpesvirus 1 DNA by the nested polymerase chain reaction

Veterinary Microbiology, 1996
The thymidine kinase region of feline herpesvirus 1 (FHV 1) genome in ocular/nasal swabs from cats with clinical manifestations of upper respiratory disease was amplified by nested polymerase chain reaction (nested PCR). Two primer pairs were prepared for nested PCR. FHV 1 DNA in ocular/nasal swabs was extracted using instaGene-DNA purification matrix.
M, Hara, M, Fukuyama, Y, Suzuki, S, Kisikawa, T, Ikeda, A, Kiuchi, K, Tabuchi   +6 more
openaire   +2 more sources

Evidence of feline herpesvirus-1 DNA in the vestibular ganglion of domestic cats

The Veterinary Journal, 2010
In humans, herpes simplex virus type-1 has recently been detected in the vestibular ganglion (VG) and labyrinth (VL) and may be associated with vestibular signs. Feline herpesvirus-1 (FHV-1) is widespread amongst cat populations and affects many different tissues. The aim of this pilot study was to investigate the presence of FHV-1 DNA in the VG and VL
Birgit, Parzefall, Wolfgang, Schmahl, Andrea, Fischer, Andreas, Blutke, Uwe, Truyen, Kaspar, Matiasek   +5 more
openaire   +2 more sources

The domestic cat antibody response to feline herpesvirus-1 increases with age

Veterinary Immunology and Immunopathology, 2017
Herpesviruses establish lifelong infections, normally characterized by prolonged periods of latency with intermittent episodes of viral reactivation. Feline herpesvirus-1 (FHV-1) infects domestic cats, and epidemiological studies indicate that many or most domestic cats are exposed to FHV-1, but the strength and longevity of the antibody response to ...
Michael W, Munks, Alana M, Montoya, Cameron M, Pywell, Garrick, Talmage, Anna, Forssen, Teresa L, Campbell, Donald D, Dodge, John W, Kappler, Philippa, Marrack   +8 more
openaire   +2 more sources

The recombinant feline herpesvirus 1 expressing feline Calicivirus VP1 protein is safe and effective in cats

Vaccine
Feline herpesvirus type 1 (FHV) and feline calicivirus (FCV) are significant pathogens causing upper respiratory tract disease in cats. Existing inactivated or modified live vaccines against FCV and FHV face limitations in safety and efficacy. To overcome these challenges, a recombinant strain FHV ΔgI/gE-FCV VP1 was developed by deleting the gI/gE gene
Aoxing, Tang, Meng, Zhu, Jie, Zhu, Da, Zhang, Shiqiang, Zhu, Chunchun, Meng, Chuanfeng, Li, Guangqing, Liu   +7 more
openaire   +2 more sources

Effects of cidofovir on cell death and replication of feline herpesvirus-1 in cultured feline corneal epithelial cells

American Journal of Veterinary Research, 2005
Abstract Objective — To assess the effect of cidofovir on viability of feline corneal epithelial (FCE) cells, replication of feline herpesvirus (FHV)-1, and virus-induced cytopathic changes. Sample Population —Healthy
Lynne S, Sandmeyer, Charlotte B, Keller, Dorothee, Bienzle   +2 more
openaire   +2 more sources