Results 251 to 260 of about 240,911 (364)

DNA‐binding properties of non‐intercalating water‐soluble organometallic Ir(III) luminophores

open access: yesChemistry – A European Journal, Accepted Article.
A series of Ir(III) complexes, [Ir(C^N)2(en)]+ (where C^N = 2‐phenyl‐benzo[d]thiazolyl cyclometalating ligand; en = ethylene diamine), are reported with structural variation via a substituent (H, Me, OMe, Cl, OCF3) at the coordinated phenyl ring.
Ibrahim Alkhaibari   +4 more
wiley   +1 more source

Novel Microwave Plasma Source for Plasma Chemistry in Gases

open access: yesChemie Ingenieur Technik, EarlyView.
A new microwave plasma source for plasma gas chemistry is introduced. Microwave energy is specifically coupled into defined gas volumes to activate chemically internal compounds such as N2, CO2 or H2O. The activation of N2 and the conversion of CO2 to CO are given as examples.
Andreas Schulz   +6 more
wiley   +1 more source

Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a Pan‐Degrader

open access: yesChemMedChem, EarlyView.
This study introduced DCAF11 as an E3 ligase for PROTAC‐mediated histone deacetylase (HDAC) degradation. By replacing cereblon with DCAF11 as recruited E3 ligase, a selective HDAC6 degrader (A6) was transformed into pan‐HDAC degraders. The lead compound, 1j (FF2039), potently degraded HDACs from classes I, IIa, and IIb, showing strong antiproliferative
Felix Feller   +5 more
wiley   +1 more source

Fracturing behaviors of flawed granite induced by dynamic loadings: A study based on DIP and PFC

open access: yesDeep Underground Science and Engineering, EarlyView.
This research examines granite's mechanical properties under split‐Hopkinson pressure bar testing, focusing on factors such as grain size and flaw dimensions. The study reveals that tension cracks are prevalent across grain sizes, with most intergrain cracks occurring between feldspar and quartz.
Xiao Wang   +5 more
wiley   +1 more source

A review of multiscale numerical modeling of rock mechanics and rock engineering

open access: yesDeep Underground Science and Engineering, EarlyView.
Multiscale numerical methods of rock mechanics and rock engineering are reviewed, and the review results show that more attention should be paid to the development of an advanced constitutive model in addition to numerical techniques themselves. Abstract Rock is geometrically and mechanically multiscale in nature, and the traditional phenomenological ...
Xindong Wei, Zhe Li, Gaofeng Zhao
wiley   +1 more source

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