Results 81 to 90 of about 9,467,185 (303)

Anti-CD3 monoclonal antibody in treating patients with type 1 diabetes: an updated systematic review and meta-analysis

open access: yesCardiovascular Diabetology
Objective To evaluate the efficacy of anti-CD3 monoclonal antibody (mAb) in patients with type 1 diabetes (T1D) and identify the influencing factors.
Qi Wu   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Breast density in polycystic ovarian syndrome patients: A case-control study

open access: yesInternational Journal of Reproductive BioMedicine, 2019
Background Epidemiological studies suggested a positive relationship between breast density and risk of breast cancer. One of the common hormonal disorders in women's reproductive age is polycystic ovarian syndrome (PCOS) and the results from the ...
Bita Eslami   +4 more
doaj   +1 more source

Female coaches in strength and conditioning: Why so Few? [PDF]

open access: yes, 2019
A substantial issue in sporting professions today, including elite strength and conditioning is gender imbalance. Attitudes towards women’s roles are complex and institutionally entrenched, contributing to barriers to women’s success. While real issues
O'Malley, Lynne Marie
core  

Does the gender composition of scientific committees matter? [PDF]

open access: yes, 2017
We analyze how a larger presence of female evaluators affects committee decision-making using information on 100,000 applications to associate and full professorships in Italy and Spain.
Bagues, Manuel F.   +2 more
core   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Defective Homologous Recombination Repair By Up‐Regulating Lnc‐HZ10/Ahr Loop in Human Trophoblast Cells Induced Miscarriage

open access: yesAdvanced Science
Human trophoblast cells are crucial for healthy pregnancy. However, whether the defective homologous recombination (HR) repair of dsDNA break (DSB) in trophoblast cells may induce miscarriage is completely unknown.
Weina Chen   +11 more
doaj   +1 more source

The Impact of Female Attractiveness in Spy [PDF]

open access: yes, 2017
This thesis discusses the impact of female attractiveness on the female character which is related to the way Spy sees attractive women and what the impacts to them are.
Handojo, P. F. (Priska)   +1 more
core  

Psychometric properties of Basic Empathy Scale among female juvenile delinquents and school youths [PDF]

open access: yes, 2017
Research on empathy often distinguishes between affective and cognitive empathy, but there is limited knowledge regarding the application or measurement of these two dimensions of empathy among female youth, especially forensic samples of female youth ...
Gonçalves, Rui Abrunhosa   +3 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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